4-Chlormethyl-5-methyl-1,3-dioxol-2-on
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- CAS-Nr.
- 80841-78-7
- Bezeichnung:
- 4-Chlormethyl-5-methyl-1,3-dioxol-2-on
- Englisch Name:
- 4-Cloromethyl-5-methyl-1,3-dioxol-2-one
- Synonyma:
- DMDO-CL;4-CHLOROMETHYL-5-METHYL-1,3-DIOXOL-2-ONE;Olmesartan impurity;4-ChloroMethyl-5-Methyl-1;4-chloromethyl-5-methyl-1,3-dioxolane-2-one;AZATMint-C;DMDO-Chloride;Olmesartan Impurity 3;Olmesartan Impurity 57;Olmesartan Medoxomil IMP
- CBNumber:
- CB4416605
- Summenformel:
- C5H5ClO3
- Molgewicht:
- 148.54
- MOL-Datei:
- 80841-78-7.mol
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4-Chlormethyl-5-methyl-1,3-dioxol-2-on Eigenschaften
- Siedepunkt:
- >90℃/2mm
- Dichte
- 1.362±0.06 g/cm3(Predicted)
- Brechungsindex
- 1.4760-1.4820
- Flammpunkt:
- 129 °C
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- L?slichkeit
- Chloroform (Slightly), Methanol (Slightly)
- Aggregatzustand
- liquid
- Wichte
- 1.36
- Farbe
- Colorless to Light yellow to Light orange
- BRN
- 4798926
- InChI
- InChI=1S/C5H5ClO3/c1-3-4(2-6)9-5(7)8-3/h2H2,1H3
- InChIKey
- QCLFSYYUWPUWQR-UHFFFAOYSA-N
- SMILES
- CC1=C(OC(=O)O1)CCl
- CAS Datenbank
- 80841-78-7(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22-36/37/38 |
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| S-S?tze: |
26 |
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| WGK Germany |
3 |
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| HS Code |
29329990 |
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| Speicherklasse |
10 - Combustible liquids |
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| Hazard Classifications |
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
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| Bildanzeige (GHS) |
 
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 3 |
Achtung |
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P264, P270, P301+P310, P321, P330,P405, P501 |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
| P405 |
Unter Verschluss aufbewahren. |
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4-Chlormethyl-5-methyl-1,3-dioxol-2-on Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
4-Chloromethyl-5-methyl-1,3-dioxol-2-one is a useful branch side chain for synthetic penicillin esters such as Lenampicillin, Mecillinam, etc. It can improve the stability and absorption of drugs, increase biological activity, and reduce side effects. It is also used to prepare amine drugs, such as Norfloxacin prodrug. In the prior art, the primary method for synthesizing 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one is a chlorination reaction of chlorine gas or N-chlorosuccinimide.
Chemische Eigenschaften
Colorless to Light yellow to Light orange clear liquid or Pale Yellow Oil.
Verwenden
4-Chloromethyl-5-methyl-1,3-dioxol-2-one is an important reagent in the preparation of angiotensin II receptor antagonist such as Olmesratan Medoxomil (O550000). It is also used in the preparation of prodrugs of ampicillin.
4-Chlormethyl-5-methyl-1,3-dioxol-2-on Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-Chlormethyl-5-methyl-1,3-dioxol-2-on Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 610)Lieferanten
| Firmenname |
Telefon |
E-Mail |
Land |
Produktkatalog |
Edge Rate |
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Xinxiang Hongqi District Houyuan Trading Co.,Ltd
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+86-0373-3695376 +86-13937349994
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HYJM@houyuanjm.com |
China |
299 |
58 |
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Hebei Chuanghai Biotechnology Co., Ltd
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+8615350571055
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Sibel@chuanghaibio.com |
China |
8738 |
58 |
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Henan Fengda Chemical Co., Ltd
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+86-371-86557731 +86-13613820652
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info@fdachem.com |
China |
20122 |
58 |
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airuikechemical co., ltd.
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+86-18353166132
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sales02@airuikechemical.com |
China |
983 |
58 |
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Hebei Ganmiao New material Technology Co., LTD
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+86-17332992504
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sales8@hbganmiao.com |
China |
300 |
58 |
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HANGZHOU HAILAN CHEMICAL CO.,LTD.
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+86-57156122185 +86-15967590394
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sales@hailan-chem.com |
China |
2997 |
58 |
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Capot Chemical Co.,Ltd.
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+86-（0）57185586718 +86-13336195806
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sales@capot.com |
China |
29640 |
60 |
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Beijing Cooperate Pharmaceutical Co.,Ltd
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010-60279497
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sales01@cooperate-pharm.com |
CHINA |
1803 |
55 |
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Henan Tianfu Chemical Co.,Ltd.
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+86-0371-55170693 +86-19937530512
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info@tianfuchem.com |
China |
21586 |
55 |
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Shanghai Time Chemicals CO., Ltd.
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+86-021-57951555 +8617317452075
|
jack.li@time-chemicals.com |
China |
1803 |
55 |
80841-78-7(4-Chlormethyl-5-methyl-1,3-dioxol-2-on)Verwandte Suche:
- (5-Methyl-2-oxo-1,3-dioxol-4-yl)Methyl Chloride
- 4-(chloroMethyl)-5-Methyl-1,3-dioxol-2-oneSynonyMs
- 1,3-Dioxol-2-one, 4-(chloromethyl)-5-methyl-
- 4-Cloromethyl-5-methyl-1,3-dioxol-2-one
- 4-CloroMethyl-5-Methyl-1,3-dioxol-2-one (DMDO-Cl)
- OlMesartan IMpurity (4-(ChloroMethyl)-5-Methyl-1,3-Dioxol-2-one)
- 4- chloroMethyl-5- Methyl-1,3- two oxygenheterocyclicpentadiene-2- ketone
- -5--1,3- two4-chloroMethylMethylcyclopentene-2- ketoneheterocyclic oxygen
- 4-ChloroMethyl-5-Methyl-l,3-dioxocyclopenten-2–one
- DMDO-CL: 4-(chloromethyl)-5-methyl-1,3-dioxol-2-one
- Olmesartan Medoxomil IMP
- 4-( Cyclomethyl carbonyl ) -5 - methyl – 1,3-dioxol-2-one ( OLM 45 )
- 4-CHLOROMETHYL-5-METHYL-2-OXO-1,3-DIOXOLE
- 4-CHLOROMETHYL-5-METHYL-1,3-DIOXOLEN-2-ONE
- DMDO CL (4-METHYL-5-CHLOROMETHYL-1,3-DIOXOL-2-ONE)
- 4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One(Dmdo-Cl)
- 4-Chloromethyl-5-Methyl-1,3-Dioxocyclopenten-2-one
- 4-Chloromethyl-5-methyl-2H-1,3-dioxol-2-one
- 4-Choromethyl-5-methyl-2-oxo-1,3-dioxole
- 4-Chloromethyl-5-Methyl-1,3-Di
- 4-CHLOROMETHYL-5-METHYL-1,3-DIOXOL-3-ONE
- 4-methyl-5-chloro methyl-1,3-dioxol-2-one
- 4-CHLOROMETHYL-5-METHYL-1,3-DIOXOL-2-ONE (INTERMEDIATE OF OLMESARTAN MEDOXOMIL)
- 4-Chloromethyl-5-methyl-1,3-dioxol-2-on
- 4-CHLOROMETHYL-5-METHYL-1,3-DIOXOL-2-ONE HPLC 95%
- 4-Methyl-5-(chloromethyl)-1,3-dioxole-2-one
- 4-chloroMethyl-5-Methyl-1,3-dioxdene-2-one
- Olmesartan Medoxomil Impurity 5
- Olmesartan Medoxomil Impurity 56
- 4-Cloromethyl-5-methyl-1,3-dioxol-2-one in stock Factory
- Olmesartan Impurity 3
- AZATMint-C
- Olmesartan Impurity 57
- 4-chloromethyl-5-methyl-1,3-Dioxol-2-oneQ: What is
4-chloromethyl-5-methyl-1,3-Dioxol-2-one Q: What is the CAS Number of
4-chloromethyl-5-methyl-1,3-Dioxol-2-one Q: What is the storage condition of
4-chloromethyl-5-methyl-1,3-Dioxol-2-one Q: What are the applications of
4-chloromethyl-5-methyl-1,3-Dioxol-2-one
- Olmesartan Medoxomil EP Impurity
- 4-Cloromethyl-5-methyl-1,3-dioxol-2-one ISO 9001：2015 REACH
- Olmesartan Chloromethyl Impurity
- 4-Chloromethyl-5-methyl-1,3-dioxol-2-one >
- Olmesartan Medoxomil Impurity 5
(4-(Chloromethyl)-5-methyl-1,3-Dioxol-2-one)
- 4-ChloroMethyl-5-Methyl-1
- 4-CHLORO METHYL-5-METHYL-1,3-DAIOXOL,2-ONE(DMDO.CL)
- 4,5- dinmethyl-1,3-dioxol-2-
- 4-ChlDMDO-Cloromethyl-5-methyl-1,3-dioxol-2-one
- 4-Chloromethyl-5-methyl-1,3-Dioxole -2-one (DMDO CL)
- 4-Chloromethyl-5-MethyI-1 ,3-Diox0l-2-One(DMDO-CI)
- 4-Chlomethyl-5-methy1-1,3,dioxol-2-one
- Olmesartan Medoxomil Impurity 5
(5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl Chloride
- 4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One(DMDO-CI)
- 4-Chloromethyl-5-methyl-1,3-dioxl-2-one
- DMDO-Chloride
- 4-Chloromethyl-5-methyl-1,3-Dioxol-2-one (DMDO Chloride )
- 4-chloromethyl-5-methyl-1,3-dioxolane-2-one
- 4-CHLOROMETHYL-5-METHYL-1,3-DIOXOL-2-ONE
- DMDO-CL
- Olmesartan impurity
- 80841-78-7
- 44690-92-6
- C5H5ClO3
