Milnacipran Hydrochloride
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- CAS-Nr.
- 101152-94-7
- Englisch Name:
- Milnacipran Hydrochloride
- Synonyma:
- IXEL;F 2207;Dalcipran;TOLEDOMIN;cis-(+-)-d;MIDALCIPRAN;MLNACIPRAM HCL;Milnacipran HCI;MILNACIPRAN HCL;Chiral Reagents
- CBNumber:
- CB4423243
- Summenformel:
- C15H23ClN2O
- Molgewicht:
- 282.81
- MOL-Datei:
- 101152-94-7.mol
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Milnacipran Hydrochloride Eigenschaften
- Schmelzpunkt:
- 179-1810C
- Flammpunkt:
- 9℃
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: 19 mg/mL
- Aggregatzustand
- solid
- Farbe
- white
- Wasserl?slichkeit
- H2O: 19mg/mL
- Merck
- 14,6194
- InChI
- InChI=1/C15H22N2O.ClH/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12;/h5-9,13H,3-4,10-11,16H2,1-2H3;1H/t13-,15+;/s3
- InChIKey
- XNCDYJFPRPDERF-DPKVYHSMNA-N
- SMILES
- [C@@]1(C(=O)N(CC)CC)(C[C@H]1CN)C1C=CC=CC=1.Cl |&1:0,9,r|
- CAS Datenbank
- 101152-94-7(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn,T,F |
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| R-S?tze: |
22-39/23/24/25-23/24/25-11 |
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| S-S?tze: |
7-16-36/37-45 |
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| RIDADR |
UN 2811 6.1/PG 3 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
GZ1014010 |
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| HazardClass |
6.1 |
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| PackingGroup |
III |
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| HS Code |
29242990 |
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| Speicherklasse |
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects |
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| Hazard Classifications |
Acute Tox. 3 Oral |
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| Toxizit?t |
LD50 orally in mice: 237 mg/kg (Bonnaud) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 3 |
Achtung |
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P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
| P301+P310 |
BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
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Milnacipran Hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
Chemische Eigenschaften
Crystalline Solid
Verwenden
Milnacipran Hydrochloride is an antidepressant. A selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia.
Allgemeine Beschreibung
Milnacipran Hydrochloride, sold under the brand names Savella, Ixel, Dalcipran, or Toledomin, is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the treatment of depression. In 2009, the US Food and Drug Administration (FDA) approved milnacipran for management of the chronic pain disorder fibromyalgia, making it only the third drug approved in the US for this indication besides duloxetine and pregabalin.
Biologische Aktivit?t
Orally active 5-HT and noradrenalin re-uptake inhibitor (SNRI) (IC 50 values are 203 and 100 nM respectively) that displays no affinity at a range of other receptors. Causes adaptive changes to α 1 -adrenergic and 5-HT 2A serotonergic systems when administered repeatedly. Exhibits antidepressive and antinociceptive activities in vivo .
Milnacipran Hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Milnacipran Hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 365)Lieferanten
101152-94-7()Verwandte Suche:
[4S-(4α,4aα,5aα,12aα)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxonaphthacen-2-carboxamidmonohydrochlorid
Terconazol
Mianserinhydrochlorid
Aciclovir
- cis-(+-)-2-(aminomethyl)-n,n-diethyl-1-phenylcyclopropanecarboxamidemonohydr
- cis-(+-)-d
- Milnacipran Hydrochloride (Subject to patent free)
- (1R,2S)-rel-2(Amino-methyl)-N,N-diethyl-1-phenyl-cyclopropanecarboxamide, Monohydrochloride
- Dalcipran
- F 2207
- (1R,2S)-REL-2-(AMINOMETHYL)-N,N-DIETHYL-1-PHENYLCYCLOPROPANECARBOXAMIDE HYDROCHLORIDE
- (1R,2S)-REL-2-(AMINOMETHYL)-N,N-DIMETHYL-1-PHENYLCYCLOPROPANECARBOXAMIDE HYDROCHLORIDE
- Milnacipran hydrochloride solution
- F 2207, Midalcipran, Toledomin, (1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide monohydrochloride
- rel-2α*-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1α*-carboxamide·hydrochloride
- rac Milnacipran Hydrochloride
- (1R*,2S*)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamidehydrochloride
- Milnacipran HCI
- Milnacipran Hydrochloride Tablets
- Milnacipran HCl (1)
- TOLEDOMIN
- MILNACIPRAN HCL
- MILNACIPRAN HYDROCHLORIDE
- MIDALCIPRAN
- MIDALCIPRAN HYDROCHLORIDE
- 1-phenyl-1-(diethylaminocarbonyl)-2-(aminomethyl)cyclopropanehydrochloride
- 2-(aminomethyl)-n,n-diethyl-1-phenyl-cyclopropanecarboxamidmonohydrochlori
- 2-(aminomethyl)-N,N-diethyl-1-phenyl-1-cyclopropanecarboxamide hydrochloride
- Milnacipran-d5 HCl (and Enantiomer)
- Milancipran Hydrochloride
- MilnacipranHydrochloride>
- Milnacipran Hydrochloride (250 mg)
- Cyclopropanecarboxamide, 2-(aminomethyl)-N,N-diethyl-1-phenyl-, hydrochloride (1:1), (1R,2S)-rel-
- Milnacipran Hydrochloride Impurities
- Milnacipran hydrochlorideQ: What is
Milnacipran hydrochloride Q: What is the CAS Number of
Milnacipran hydrochloride Q: What is the storage condition of
Milnacipran hydrochloride Q: What are the applications of
Milnacipran hydrochloride
- Chiral Reagents
- Milnacipran hydrochloride, 98%, Serotonin and norepinephrine reuptake inhibitor
- RSYYMilnacipranhydrochloride
- Minapram hydrochloride
- MLNACIPRAM HCL
- Milnacipran hydrochloride in acetonitrile
- Milnacipran hydrochloride, Serotonin and norepinephrine reuptake inhibitor
- Milnacipran hydrochloride, 10 mM in DMSO
- Milnacipran HCl - Bio-X ?
- Milnacipran hydrochloride【M1318】
- Milnacipran Hydrochloride 1.0 mg/ml in Methanol (as free base)
- D5-Milnacipran HCl
- Milnacipran hydrochloride (Standard)
- IXEL
- 101152-94-7
- C15H22N2OHClC15H23ClN2O
- C15H23ClN2O
- NEGGRAM
- Amines
- Aromatics
- Chiral Reagents
- Antibiotic Explorer
- Intermediates & Fine Chemicals
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