3-α,6-α-Dihydroxy-5-β-cholan-24-sure
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- CAS-Nr.
- 83-49-8
- Bezeichnung:
- 3-α,6-α-Dihydroxy-5-β-cholan-24-sure
- Englisch Name:
- Hyodeoxycholic acid
- Synonyma:
- HDCA;Hyodeoxycholic;HYDROCHOLIC ACID;Iodeoxycholic acid;HYODESOXYCHOLIC ACID;α-Hyodeoxycholic Acid;Hyodeoxycholic acid(HDCA);3a,6a-Dihydroxy-5b-Cholan-24-Oic Acid;Nsc60672;HyodeoxychoL
- CBNumber:
- CB4462501
- Summenformel:
- C24H40O4
- Molgewicht:
- 392.58
- MOL-Datei:
- 83-49-8.mol
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3-α,6-α-Dihydroxy-5-β-cholan-24-sure Eigenschaften
- Schmelzpunkt:
- 200-201 °C (lit.)
- alpha
- D20 +8° (alc)
- Siedepunkt:
- 437.26°C (rough estimate)
- Dichte
- 0.9985 (rough estimate)
- Brechungsindex
- 1.4460 (estimate)
- storage temp.
- Refrigerator
- L?slichkeit
- Solubility in methanol, very faint turbidity. Slightly soluble in alcohol, acetone, ether and very slightly soluble in chloroform.
- pka
- 4.76±0.10(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Wasserl?slichkeit
- 5.889mg/L(25 ºC)
- Merck
- 14,4857
- InChIKey
- DGABKXLVXPYZII-SIBKNCMHSA-N
- SMILES
- C[C@]12CC[C@@H](O)C[C@@]1([H])[C@@H](O)C[C@@]1([H])[C@]3([H])CC[C@]([H])([C@H](C)CCC(=O)O)[C@@]3(C)CC[C@]21[H] |&1:1,4,7,9,12,14,18,20,27,31,r|
- CAS Datenbank
- 83-49-8(CAS DataBase Reference)
3-α,6-α-Dihydroxy-5-β-cholan-24-sure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R40:Verdacht auf krebserzeugende Wirkung.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S22:Staub nicht einatmen.
Chemische Eigenschaften
White Solid
Verwenden
Protected β-Hyodeoxycholic Acid (H998105), a potential bile acid metabolite.
Definition
ChEBI: A member of the class of 5beta-cholanic acids that is (5beta)-cholan-24-oic acid substituted by alpha-hydroxy groups at positions 3 and 6.
Allgemeine Beschreibung
Hyodeoxycholic acid is a naturally occurring secondary bile acid. It is produced by the gut flora in the small intestine. Hyodeoxycholic acid is obtained from chenodeoxycholic acid during enterohepatic circulation of bile in rats.
l?uterung methode
Crystallise -hyodeoxycholic acid from EtOAc or Me2CO. The K salt separates in needles from an alcoholic solution of the acid when an equivalent of KOMe is added (see lithocholic acid). [Weiland & Gumlish Hoppe Seyler's Z Physiol Chem 215 18 1933, Windaus & Bohne Justus Liebigs Ann Chem 433 278 1923, Beilstein 10 III 1631.]
3-α,6-α-Dihydroxy-5-β-cholan-24-sure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-α,6-α-Dihydroxy-5-β-cholan-24-sure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 582)Lieferanten
83-49-8(3-α,6-α-Dihydroxy-5-β-cholan-24-sure)Verwandte Suche:
- 7-deoxyhyocholicacid
- alpha-hyodeoxycholicacid
- 3α,6α-Dihydroxy-5β-cholanoic acid
- 3à,6à-dihydroxy-5á-cholan-24-oic acid
- HYODEOXYCHOLIC ACID FREE ACID
- HYODEOXYCHOLIC ACID 98%
- Cholan-24-oic acid, 3,6-dihydroxy-,(3α,5β,6α)-
- 3α, 6α-dihydroxycholanic acid
- 3.alpha.,6.alpha.-Dihydroxycholanic acid
- 5.beta.-Cholan-24-oic acid, 3.alpha.,6.alpha.-dihydroxy-
- Cholan-24-oic acid, 3,6-dihydroxy-, (3.alpha.,5.beta.,6.alpha.)-
- Nsc60672
- HYODEOXYCHOLIC ACID (RG)
- Hyodeoxycholic acid,3α,6α-Dihydroxy-5β-cholan-24-oic acid
- Pig deoxybile acid
- 4-{5,9-dihydroxy-2,15-diMethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl}pentanoic acid
- 4-[(2R,5R,7R,8S,14R,15R)-5,8-dihydroxy-2,15-diMethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanoic acid
- hyodeoxycholic acid GMP
- 6-alpha-hydroxylithocholicacid
- Hyodesoxycholic Acid (HDCA)
- alpha-HYDROXYDEOXYCHOLIC ACID
- (4R)-4-((3R,5R,6S,10R,13R,17R)-3,6-dihydroxy-10,13-diMethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
- Hyodeoxycholic acid, >=98%
- (R)-4-((3R,5R,6S,8S,9S,10R,13R,14S,17R)-3,6-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
- (4R)-4-((3R,5R,6S,10R,13R,17R)-3,6-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phena
- 5BETA-CHOLAN-24 OIC ACID-3ALPHA,6ALPHA-DIOL
- 5-BETA-CHOLANIC ACID-3-ALPHA, 6-ALPHA-DIOL
- 3ALPHA, 6ALPHA-DIHYDROXY-5BETA-CHOLANIC ACID
- 3-ALPHA,6-ALPHA-DIHYDROXY-5-ALPHA-CHOLAN-24-OIC ACID
- 3ALPHA,6ALPHA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID
- ALPHA-HYODESOXYCHOLIC ACID
- HYODEOXYCHOLANIC ACID
- HYODEOXYCHOLIC ACID
- 3,6-dihydroxy-,(3alpha,5beta,6alpha)-cholan-24-oicaci
- 3-alpha,6-alpha-dihydroxy-5-beta-cholan-24-oicaci
- 4-(3,6-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
- 3alpha,6alpha-Dihydroxy-5beta-cholanoic acid
- 3α,6α-dihydroxy-5β-cholanic acid
- HyodeoxychoL
- Hyodeoxycholicacid,96%
- (3R,5R,6S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-5-methylhex-5-en-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,6-diol
- Cholan-24-oic acid, 3,6-dihydroxy-, (3α,5β,6α)-
- Hyodeoxycholic acid USP/EP/BP
- 3α, 6α-Dihydroxy-5beta-cholan-24-oic acid
- Iodeoxycholic acid
- Hyodeoxycholic acid(HDCA)
- HYDROCHOLIC ACID
- α-Hyodeoxycholic Acid
- 3α,6α-Dihydroxy-5β-cholan-24-oic acid
- 3a,6a-Dihydroxy-5b-Cholan-24-Oic Acid
- HYODESOXYCHOLIC ACID
- Deoxycholic Acid Impurity 4(α-Hyodeoxycholic Acid)
- 5β-CHOLANIC ACID-3α, 6α-DIOL
- 3a,6a-Dihydroxy-5beta-cholan-24-oic acid
- Apigenine Impurity 2
- 5β-Cholan-24-Oic Acid-3α,6α-Diol
- Hyodeoxycholic acid, 10 mM in DMSO
- D5-α-Hyodeoxycholic Acid
