ANTI-UNCOUPLING PROTEIN 1 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-UCP-1 antibody produced in rabbit has been used in western blotting and immunohistochemistry.
Allgemeine Beschreibung
Uncoupling protein (UCP1) is a 32 kDa, mitochondrial inner membrane protein. It is active as a proton channel forming dimer. It can bind purine nucleotides and is capable of being stimulated by fatty acids.
Biochem/physiol Actions
Uncoupling proteins (UCPs) are transporters functioning as enzymatic uncouplers of oxidative phosphorylation. They can return protons pumped by the respiratory chain to the mitochondrial matrix. UCP-1 is exclusively expressed in brown adipose tissue (BAT) in rodents and in neonates where it is regulated by norepinephrine and thyroid hormones. UCP-1 has been shown to depend on CoQ (ubiquinone) as an obligatory co-factor.
ANTI-UNCOUPLING PROTEIN 1 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
