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Mannitol

Mannitol Struktur
87-78-5
CAS-Nr.
87-78-5
Bezeichnung:
Mannitol
Englisch Name:
Mannitol
Synonyma:
MANNITOL USP;Hexahydroxyhexane;Maitol;MANNITOL BP;DL-Mannitol;Cordycepin 10% Mannitol;NSC 9256;MANNITOL;MANNITOL B;Mannidex 16700
CBNumber:
CB4720971
Summenformel:
C6H14O6
Molgewicht:
182.17
MOL-Datei:
87-78-5.mol

Mannitol Eigenschaften

Schmelzpunkt:
167°C
Siedepunkt:
494.9°C
Dichte
1.596
Brechungsindex
1.5970 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
pka
pKa 13.50(H2O,t =18)(Approximate)
Aggregatzustand
Solid
Farbe
White to off-white
Wasserl?slichkeit
177.3g/L(25 ºC)
Dielectric constant
3.0(22℃)
Erinnerung an die inhaltsstoffe
Mannitol (87-78-5)
InChI
InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
InChIKey
FBPFZTCFMRRESA-KVTDHHQDSA-N
SMILES
OC[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
CAS Datenbank
87-78-5(CAS DataBase Reference)
EPA chemische Informationen
Mannitol (87-78-5)

Sicherheit

TSCA  TSCA listed
HS Code  29054300

Mannitol Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

It can be used to lower intraocular pressure and in the postoperational period in ophthalomological procedures as well as during brain edema.

Chemische Eigenschaften

D-mannitol (D-mannohexan-1.2.3.4.5.6-hexaol) is a constituent of several plants including the Manna ash, several edible plants, and seaweed. Parts of the latter contain up to 10 % mannitol by weight. The solubility in water is approximately 230 g/L at room temperature and it increases with increasing temperature. Mannitol is stable under the common processing conditions of foods.
Mannitol is approximately 50 % as sweet as sucrose and non-cariogenic. In the European Union, maltitol is approved as E 421 for a large number of food applications. In the United States, mannitol produced by hydrogenation of glucose or fructose solutions or by fermentation by Zygosaccharomyces rouxii or Lactobacillus intermedius is approved for several food applications. It is also approved in many other countries.

Verwenden

Mannitol is a polyol (polyhydric alcohol) produced from hydrogena- tion from fructose that functions as a sweetener, humectant, and bulking agent. it has low hygroscopicity and poor oil solvency. it has 1.6 kcal/g. it is approximately 22% soluble in water and is approximately 72% as sweet as sugar, exhibiting a cool, sweet taste. it functions as a dusting agent with starch in chewing gum. it is used in sugarless candy, chewing gum, cereal, and pressed mints.

Definition

mannitol: A polyhydric alcohol,CH2OH(CHOH)4CH2OH, derived frommannose or fructose. It is the mainsoluble sugar in fungi and an importantcarbohydrate reserve in brownalgae. Mannitol is used as a sweetenerin certain foodstuffs and as a diureticto relieve fluid retention.

Mechanism of action

Today, mannitol is the most widely used osmotic diuretic. It raises osmotic pressure in renal tubules, thus reducing reabsorption of water in the nephrons. As a result, a large quantity of free water is released, sodium secretion increases, and as a rule, an insignificant amount of potassium is secreted. Mannitol is used as an adjuvant drug for preventing oliguria and anuriua.

Clinical Use

Mannitol is the agent most commonly used as an osmotic diuretic. Sorbitol also can be used for similar reasons.Mannitol is administered intravenously in solutions of 5 to 50% at a rate of administration that is adjusted to maintain the urinary output at 30 to 50 ml/hour. Mannitol is filtered at the glomerulus and is poorly reabsorbed by the kidney tubule. The osmotic effect of mannitol in the tubule inhibits the reabsorption of water, and the rate of urine flow can be maintained. It also is used to reduce intracranial pressure by reducing cerebral intravascular volume.

Sicherheitsprofil

A poison by intravenous route. Human systemic effects. When heated to decomposition it emits acrid smoke and irritating vapors.

Mannitol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Mannitol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 502)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763
sales@tnjchem.com China 34563 58
Hebei Jingbo New Material Technology Co., Ltd
+8619931165850
hbjbtech@163.com China 1000 58
Nanjing Deda New Material Technology Co., Ltd
+8613223293093
bella@njdeda.com China 80 58
Hebei Chuanghai Biotechnology Co., Ltd
+86-15350571055
Sibel@chuanghaibio.com China 6085 58
Shandong Deshang Chemical Co., Ltd.
+86-0531-8875-2665 +8613153039501
info@deshangchem.com China 661 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055
Sibel@chuanghaibio.com China 8738 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-86-13131129325 +8613131129325
sales1@chuanghaibio.com China 5229 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615531151365
mina@chuanghaibio.com China 18126 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971
deasea125996@gmail.com China 2472 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651
admin@zlchemi.com China 3692 58

87-78-5(Mannitol)Verwandte Suche:


  • MANNITOL
  • MANNITOL USP/BP
  • MANNITOL PYROGEN FREE USP24
  • MANNITOL PYROGEN FREE USP.
  • MANNITOL B
  • MANNITOL USP 24
  • N.F,USP MANNITOL
  • MANNITOL, CP2000/BP2000/USP23
  • Mannidex 16700
  • Mannitol (8CI, 9CI)
  • NSC 9256
  • Mannitol###D-Mannitol
  • D-glycero-Hexitol
  • Mannitol, 98%, from Phaeophyta
  • mannitol crystalline powder
  • Mannitol crystals
  • Mannitol/Mannitol powder
  • Mannitol USP/EP/BP
  • Mannitol CAS 87 78 5
  • D-Mannitol Powder CAS?87-78-5?Pharmaceutical Grade Mannitol Powder
  • Mannitol(87-78-5)
  • Cordycepin 10% Mannitol
  • MANNITOL BP
  • rel-(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexaol
  • PEARLITOL 200SD
  • PEARLITOL 160C
  • Cocaine Hydrochloride Impurity 1(Cocaine Hydrochloride EP Impurity A )
  • DL-Mannitol, 10 mM in DMSO
  • Mannose Impurity 21 (Mannitol)
  • Maitol
  • DL-Mannitol (Standard)
  • DL-Mannitol
  • Hexahydroxyhexane
  • MANNITOL USP
  • 87-78-5
  • 87-78-5
  • Elisa Kit-plant ELISA Kit
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