BISINDOLYLMALEIMIDE III

137592-43-9

CAS-Nr.: 137592-43-9

Englisch Name:: BISINDOLYLMALEIMIDE III

Synonyma:: BISINDOLYLMALEIMIDE III;Bisindolylmaleimide III, 10 mM in DMSO;Bisindolylmaleimide III, PKC inhibitor;3-[1-(3-aminopropyl)indol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione;3-(1-(3-Aminopropyl)-1H-indol-3-yl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-yl)-

CBNumber:: CB4728487

Summenformel:: C23H20N4O2

Molgewicht:: 384.43

MOL-Datei:: Mol file

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 42

BISINDOLYLMALEIMIDE III Eigenschaften

Siedepunkt:: 708.7±60.0 °C(Predicted)

Dichte: 1.41±0.1 g/cm3(Predicted)

L?slichkeit: DMSO: soluble; Methanol: soluble

Aggregatzustand: A crystalline solid

pka: 8.15±0.60(Predicted)

Farbe: Brown to reddish brown

Sicherheit

BISINDOLYLMALEIMIDE III Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Bisindolylmaleimide III was developed as a protein kinase C (PKC) inhibitor with structural similarity to the nonspecific PKC inhibitor staurosporine. At 1 μM, bisindolylmaleimide III inhibits 93% of PKCα kinase activity and also inhibits many other protein kinases including, S6K1, MAPKAP-K1, RSK2 and MSK1 with similar potency. Additionally, it inhibits PDK1, an important kinase in the insulin signaling pathway, with an IC₅₀ value of 3.8 μM.

Verwenden

Bisindolylmaleimide III is a protein kinase C inhibitor and was also shown to exhibit inhibitory activities towards PDK1, an important kinase in the insulin signaling pathway,

BISINDOLYLMALEIMIDE III Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

BISINDOLYLMALEIMIDE III Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 42)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
J & K SCIENTIFIC LTD.	18210857532; 18210857532	jkinfo@jkchemical.com	China	96815	76
Shanghai TaoSu Biochemical Technology Co., Ltd.	021-33632979	info@tsbiochem.com	China	8065	58
BOC Sciences	16314854226	info@bocsci.com	United States	9923	65
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9804	58
Shanghai YuanYe Biotechnology Co., Ltd.	021-61312847 13636370518	shyysw007@163.com	China	89686	60
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	9694	55

BISINDOLYLMALEIMIDE III
3-[1-(3-aminopropyl)indol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione
1H-Pyrrole-2,5-dione, 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-yl)-
3-(1-(3-Aminopropyl)-1H-indol-3-yl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione
Bisindolylmaleimide III, PKC inhibitor
Bisindolylmaleimide III, 10 mM in DMSO
137592-43-9
Amines, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals

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