1-Adamantan-ammoniumchlorid
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- CAS-Nr.
- 665-66-7
- Bezeichnung:
- 1-Adamantan-ammoniumchlorid
- Englisch Name:
- 1-Adamantanamine hydrochloride
- Synonyma:
- AMANTADINE HCL;AMANTADINE HYDROCHLORIDE;1-AMINOADAMANTANE HYDROCHLORIDE;ADAMANTANAMINE HYDROCHLORIDE;symmetrel;1-ADAMANTANAMINE HCL;ADAMANTAN-1-AMINE HYDROCHLORIDE;Mantadan;Amantadine hydrochlorid;(3s,5s,7s)-adamantan-1-amine hydrochloride
- CBNumber:
- CB4734376
- Summenformel:
- C10H18ClN
- Molgewicht:
- 187.71
- MOL-Datei:
- 665-66-7.mol
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1-Adamantan-ammoniumchlorid Eigenschaften
- Schmelzpunkt:
- >300 °C(lit.)
- Siedepunkt:
- 308.63°C (rough estimate)
- Dichte
- 1.0276 (rough estimate)
- Brechungsindex
- 1.6100 (estimate)
- storage temp.
- Store below +30°C.
- L?slichkeit
- H2O: 50 mg/mL
- Aggregatzustand
- Fine Crystalline Powder
- Farbe
- White
- Wasserl?slichkeit
- soluble
- Sensitive
- Hygroscopic
- Merck
- 14,374
- BRN
- 4198854
- Major Application
- pharmaceutical (small molecule)
- InChI
- 1S/C10H17N.ClH/c11-10-4-7-1-8(5-10)3-9(2-7)6-10;/h7-9H,1-6,11H2;1H/t7-,8+,9-,10-;
- InChIKey
- WOLHOYHSEKDWQH-UHFFFAOYSA-N
- SMILES
- Cl[H].[H][C@@]12C[C@@]3([H])C[C@@]([H])(C1)CC(N)(C2)C3
- LogP
- -1.64 at 23℃ and pH6.3
- CAS Datenbank
- 665-66-7(CAS DataBase Reference)
- EPA chemische Informationen
- Amantadine hydrochloride (665-66-7)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22-40-20/21/22 |
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| S-S?tze: |
22-36/37-36-35-20/21 |
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| RIDADR |
UN 1759 8 / PGII |
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| WGK Germany |
3 |
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| RTECS-Nr. |
AU4375000 |
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| TSCA |
TSCA listed |
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| HazardClass |
IRRITANT |
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| HS Code |
29213000 |
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| Speicherklasse |
8A - Combustible corrosive hazardous materials |
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| Hazard Classifications |
Acute Tox. 4 Oral |
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| Toxizit?t |
LD50 orally in mice, rats: 700, 1275 mg/kg (Vernier) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
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1-Adamantan-ammoniumchlorid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
R40:Verdacht auf krebserzeugende Wirkung.
R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
Crystalline Solid
Verwenden
1-Adamantanamine hydrochloride is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extra pyramidal reactions, and for postherpetic neuralgia. It is also used an NMDA-receptor antagoinst.
Definition
ChEBI: A hydrochloride obtained by combining amantadine and hydrochloric acid in equimolar amounts.
Allgemeine Beschreibung
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Sicherheitsprofil
Human poison by ingestion. Poison by ingestion, intraperitoneal, and intravenous routes. A human teratogen with developmental abnormalities of the circulatory system. Experimental reproductive effects. Human systemic effects by ingestion: distorted perceptions, euphoria, excitement, hallucinations. When heated to decomposition it emits very toxic fumes of NO, and HCl.
l?uterung methode
Dissolve the salt in dry EtOH, add a few drops of dry EtOH saturated with HCl gas, followed by dry Et2O to crystallise the hydrochloride. Dry the salt in a vacuum. [Stetter et al. Chem Ber 93 226 1960.]
1-Adamantan-ammoniumchlorid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
1-Adamantan-ammoniumchlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 679)Lieferanten
| Firmenname |
Telefon |
E-Mail |
Land |
Produktkatalog |
Edge Rate |
|
Hangzhou Qiwei Pharmatech Co.,Ltd
|
13282840061
|
mw@qwpharmatech.com |
China |
109 |
58 |
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Huzhou Chenxi Environmental Protection Technology Co. , Ltd.
|
+8616762203950
|
1034385273@qq.com |
China |
55 |
58 |
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HANGZHOU HAILAN CHEMICAL CO.,LTD.
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+86-57156122185 +86-15967590394
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sales@hailan-chem.com |
China |
2994 |
58 |
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Hebei Chuanghai Biotechnology Co., Ltd
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+8615350571055
|
Sibel@chuanghaibio.com |
China |
8738 |
58 |
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Hebei Yanxi Chemical Co., Ltd.
|
+8618531123677
|
faithe@yan-xi.com |
China |
5853 |
58 |
|
Hebei Chuanghai Biotechnology Co,.LTD
|
+86-86-13131129325 +8613131129325
|
sales1@chuanghaibio.com |
China |
5228 |
58 |
|
Hebei Chuanghai Biotechnology Co., Ltd
|
+8615531151365
|
mina@chuanghaibio.com |
China |
18126 |
58 |
|
Nantong Guangyuan Chemicl Co,Ltd
|
+undefined17712220823
|
admin@guyunchem.com |
China |
615 |
58 |
|
Shaanxi TNJONE Pharmaceutical Co., Ltd
|
+8618092446649
|
sarah@tnjone.com |
China |
1143 |
58 |
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HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
|
+86-15350851019; +8615350851019
|
admin@86-ss.com |
China |
999 |
58 |
665-66-7(1-Adamantan-ammoniumchlorid)Verwandte Suche:
- Amantadine Hydrochloride (200 mg)
- 1-AdaMantanaMine hydrochloride, 99+% 100GR
- 1-AdaMantanaMine hydrochloride, 99+% 25GR
- 1-AdaMantanaMine hydrochloride, 99+% 5GR
- 1-adamantane amine hydrochloride
- 1-Adamantanamine Hydrochleride
- 1-Aminoadamantane Hydrochloride
Amantadine Hydrochloride
- Adamantan-1-amine hydrochloride, Tricyclo[3.3.1.1~3,7~]decan-1-amine hydrochloride, Amantadine hydrochloride
- AMantadine HCl USP
- 1-adamantylammonium chloride
- 1-adamantylazanium chloride
- 1-Aminoadamantene hydrochlorid
- adamantan-1-aminium chloride
- tricyclo[3.3.1.1(3,7)]decan-1-aminium chloride
- Tricyclo[3.3.1.13,7]decan-1-amine, hydrochloride (1:1)
- aminoadamantanehydrochloride
- exp105-1
- midantane
- mydantane
- nsc83653
- tricyclo(3.3.1.1(sup3,7))decan-1-amine,hydrochloride
- 1-Adamantanamine hydrochloride, 1-Adamantylamine hydrochloride, Amantadine hydrochloride
- 1-Adamantanamine hydrochloride, 1-Adamantylamine hydrochloride, 1-Aminoadamantane hydrochloride
- TIMTEC-BB SBB003680
- TRICYCLODECANE HYDROCHLORIDE
- 1-aminoadamantenehydrochloride
- 1-ADAMANTYLAMINE HYDROCHLORIDE
- 1-ADAMANTANAMINE HYDROCHLORIDE
- 1-ADAMANTANEAMMONIUM CHLORIDE
- adamantinehydrochloride
- adamantylaminehydrochloride
- tricyclo[3.3.1.13,7]decan-1-amine,hydrochloride
- virasol
- AMANTADINE HYDROCHLORIDE, PHARMA
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- Lysovir
- Mantadix
- Virofral
- AMANTADINEHYDROCHLORIDE,USP
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- Amazolon
- Midantan
- 1-ADAMANTANAMINE HYDROCHLORIDE, 99+%
- 1-Adamantaneammonium chloride for synthesis
- 1-Adamantanamin Hydrochlorid
- 1-Adamantanamine HydrochL
- 1-adamantylammonium
- Adamantane Hydrocloride
- 1-Adamantanamine hydrochloride intermediate
- 1-Adamantanamine Hydrochloride
[Amantadine Hydrochloride]
- Amintadine Hcl
- 1-Amantadine hydrochloride
- 1-Adamantanamine hydrochloride, 99%, antiviral and antiparkinsonian compound
- Memantine Impurity 13
- Amantadine Hydrochloride Standard
- 1-Adamantanamine Hydrochloride >
