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Simfibrat

simfibrate Struktur
14929-11-4
CAS-Nr.
14929-11-4
Bezeichnung:
Simfibrat
Englisch Name:
simfibrate
Synonyma:
CLY-503;Sinfibrate;simfibrate;Cholesolvin;simfibrate USP/EP/BP;1,3-Propanediol bis[2-(4-chlorophenoxy)-2-methylpropionate];Propane-1,3-diyl bis(2-(4-chlorophenoxy)-2-methylpropanoate);Bis[2-(4-chlorophenoxy)-2-methylpropanoic acid] 1,3-propanediyl;Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, 1,1'-(1,3-propanediyl) ester;3-[2-(4-chlorophenoxy)-2-methylpropanoyl]oxypropyl 2-(4-chlorophenoxy)-2-methylpropanoate
CBNumber:
CB4875031
Summenformel:
C23H26Cl2O6
Molgewicht:
469.35
MOL-Datei:
14929-11-4.mol

Simfibrat Eigenschaften

Schmelzpunkt:
51-53°
Siedepunkt:
bp0.03 197-200°; bp0.15 220-230°
Dichte
1.2623 (estimate)

Sicherheit

Toxizit?t LD50 in mice, rats (g/kg): 3.3-3.5; 7.3-8.0 orally (Nakanishi, J. Pharm. Soc. Japan)

Simfibrat Chemische Eigenschaften,Einsatz,Produktion Methoden

Originator

Cholesorbin,Takeda,Japan,1971

Manufacturing Process

A mixture of 22 grams of α-(p-chlorophenoxy)isobutyric acid, 3.8 grams of 1,3-propanediol, 0.5 gram of p-toluenesulfonic acid and 150 ml of xylene was refluxed. When the theoretically calculated amount of water had been removed, the xylene solution was washed with dilute aqueous sodium bicarbonate and then the xylene was distilled off. The residue was distilled under reduced pressure to give 11 grams (47% yield) of 1,3-propanediol bis[α-(p-chlorophenoxy)isobutyrate] boiling at 197° to 200°C/0.03 mm Hg.

Therapeutic Function

Antihyperlipidemic

Simfibrat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Simfibrat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 20)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167
1026@dideu.com China 9996 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207
sales@molcore.com China 49734 58
TargetMol Chemicals Inc.
+1-781-999-5354;
support@targetmol.com United States 39040 58
TargetMol Chemicals Inc.
+17819995354
marketing@targetmol.com United States 19956 58
LGM Pharma 1-(800)-881-8210
inquiries@lgmpharma.com United States 2123 70
Aikon International Limited 025-58851090 13913916777
sales01@aikonchem.com China 15949 58
TargetMol Chemicals Inc. 4008200310 15002144251
marketing@tsbiochem.com China 24958 58
Shaanxi Dideu Newmaterial Co., Ltd. 029-63373950 17392216152
1050@dideu.com China 9998 58
Biosynth Biological Technology (Suzhou) Co Ltd --
sales@biosynth.com China 6051 58

14929-11-4(Simfibrat)Verwandte Suche:


  • simfibrate
  • 1,3-Propanediol bis[2-(4-chlorophenoxy)-2-methylpropionate]
  • Bis[2-(4-chlorophenoxy)-2-methylpropanoic acid] 1,3-propanediyl
  • Cholesolvin
  • CLY-503
  • Sinfibrate
  • simfibrate USP/EP/BP
  • Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, 1,1'-(1,3-propanediyl) ester
  • Propane-1,3-diyl bis(2-(4-chlorophenoxy)-2-methylpropanoate)
  • 3-[2-(4-chlorophenoxy)-2-methylpropanoyl]oxypropyl 2-(4-chlorophenoxy)-2-methylpropanoate
  • 14929-11-4
  • C23H26Cl2O6
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