Cefaloridin
|
|
|
- CAS-Nr.
- 50-59-9
- Bezeichnung:
- Cefaloridin
- Englisch Name:
- Cephaloridine
- Synonyma:
- Sefacin;Ceporin;Ceporan;Ceflorin;Keflodin;Keflordin;Sch 11527;Cephaloridine;Cephaloridine II;Cephaloridine USP/EP/BP
- CBNumber:
- CB4875354
- Summenformel:
- C19H17N3O4S2
- Molgewicht:
- 415.48
- MOL-Datei:
- 50-59-9.mol
|
Cefaloridin Eigenschaften
- Schmelzpunkt:
- 184°C
- alpha
- D +47.7° (c = 1.25 in water)
- Dichte
- 1.3230 (rough estimate)
- Brechungsindex
- 1.6390 (estimate)
- storage temp.
- 2-8°C
- pka
- 3.2(at 25℃)
- Optische Rotation
- +47.720 (c 1.25, H2O)
- Wasserl?slichkeit
- >20g/L(21 ºC)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung
|
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H317 |
Kann allergische Hautreaktionen verursachen. |
Sensibilisierung der Haut |
Kategorie 1A |
Warnung |
|
P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
|
| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P272 |
Kontaminierte Arbeitskleidung nicht au?erhalb des Arbeitsplatzes tragen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P321 |
Besondere Behandlung |
| P333+P313 |
Bei Hautreizung oder -ausschlag: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
| P363 |
Kontaminierte Kleidung vor erneutem Tragen waschen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
|
Cefaloridin Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Antibacterial agent.
Definition
ChEBI: A cephalosporin compound having pyridinium-1-ylmethyl and 2-thienylacetamido side-groups. A first-generation semisynthetic derivative of cephalosporin C.
Weltgesundheitsorganisation (WHO)
Cefaloridine, a semi-synthetic cephalosporin antibiotic, was
introduced into medicine in 1964 for the treatment of bacterial infections. It is
considered to be the most toxic of the cephalosporins, and for this reason is now
seldom used. Nevertheless, it still remains available in certain countries and the
World Health Organization is not aware of restrictive actions taken elsewhere.
Allgemeine Beschreibung
Cephaloridine, along with cephalothin, was the first member of the synthetic cephalosporin C class of antibiotic, to be introduced clinically. It was synthesized, starting with 7-aminocephalosporanic acid, by Glaxo Research Laboratories in 1962. This drug shows strong activity against gram-positive and gramnegative bacteria and Leptospira, including benzylpenicillin-resistant strains. It has been given widely by intravenous, intramuscular, and intraspinal injection to treat a variety of infections caused by Staphylococcus, Streptococcus, Neisseria, Klebsiella, Escherichia coli, and other pathogens. Because of its renal toxicity and the development of newer and more active synthetic cephalosporins, its use is declining.
Hazard
Moderately to very toxic.
Cefaloridin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Cefaloridin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 25)Lieferanten
50-59-9(Cefaloridin)Verwandte Suche:
- Cephaloridine
- Ceflorin
- Ceporan
- N-[7-[2'-Thienyl-acetamidoceph-3-ylmethyl]] pyridinium-4-carboxylate
- pyridinium, 1-((2-carboxy-8-oxo-7-(2-(2-thienyl)acetamido)-5-thia-1-azabicyclo( 4.2.0)o ct- 2-en-3-yl)methyl)-, hydroxide, inner salt 1-[(7'-beta-[2-(2-thienyl)acetamido]-8'-oxo-1'-aza-5'-t hiabicyclo[4.2.0]-oct-2 '-en-3'-yl)methyl]pyridinium-2'-carboxylate 40602 7-((2-thienyl)acetamido)-3-(1-pyridylmethyl)cephalosporanic acid 7-(alpha-(2-thienyl)acetamido)-3-(1-pyridylmethyl)-3-cephem-4-carboxylic acid 7-(alpha-(2-thienyl)acetamido)-3-(1-pyridylmethyl)-3-cephem-4-carboxylic acid b etaine
- (6R,7R)-8-oxo-3-(pyridin-1-ylmethyl)-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- Ceporin
- Keflodin
- Keflordin
- Sefacin
- (6R,7R)-8-Oxo-3-(1-pyridiniumylmethyl)-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- PyridiniuM,1-[[(6R,7R)-2-carboxy-8-oxo-7-[[2-(2-thienyl)acetyl]aMino]-5-thia-1-azabicyclo[4.2.0]oct-
- N-(7-[2′-Thienylacetamidoceph-3-ylmethyl])pyridinium 2-carboxylate
- (6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- Cephaloridine II
- CEFALORIDINE (ALPHA FORM) USP/EP/BP
- Cephaloridine USP/EP/BP
- Sch 11527
- Enavogliflozin Impurity 32
- 50-59-9
- C19H17N3O4S4
- C19H17N3O4S2
- C19H18N3O4S2
