Posatirelin

78664-73-0

CAS-Nr.: 78664-73-0

Englisch Name:: Posatirelin

Synonyma:: RGH-2202;BRN6006446;BRN 6006446;BRN-6006446;Posatirelin;Posatirelinum;N-[(S)-6-Oxo-2-piperidinylcarbonyl]-L-Leu-L-Pro-NH2;L-Prolinamide, (2S)-6-oxo-2-piperidinecarbonyl-L-leucyl-;N-[6-Oxopiperidin-2(S)-Ylcarbonyl]-L-Leucyl-L- Prolinamide

CBNumber:: CB51179553

Summenformel:: C17H28N4O4

Molgewicht:: 352.432

MOL-Datei:: 78664-73-0.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 13

Posatirelin Eigenschaften

Schmelzpunkt:: 214-216°

alpha: D25 -80.2° (c = 1 in acetic acid)

Siedepunkt:: 739.6±60.0 °C(Predicted)

Dichte: 1.214±0.06 g/cm3(Predicted)

pka: 13.56±0.20(Predicted)

Sicherheit

Posatirelin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Posatirelin is a TRH analogue. In a rat experimental model of brain cholinergic decit by lesion of the nucleus basalis magnocellularis (nbM), posatirelin treatment rescued cholinergic neurones of the nbM and their cholinergic projections to the cerebral cortex (Sabbatini et al., 1998). Posatirelin has been used in AD and VaD patients (Parnetti et al., 1995, 1996). VaD patients treated with posatirelin showed a signicant improvement in intellectual performance, orientation, motivation and memory as compared to controls. e drug was well tolerated.

Verwenden

Posatirelin is a thyrotropin-releasing hormone analogue, used in the treatment of seizures and some neurodegenerative disease such as vascular dementia and Parkinson''s disease.

Posatirelin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

78664-34-3 2-Piperidinecarboxylic acid, 6-oxo-, 2,3,4,5,6-pentafluorophenyl ester, (2S)- L-6-HYDROXYNORLEUCINE

Downstream Produkte

Posatirelin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 13)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39039	58
Jiangsu Hongmin Pharmaceutical Co., Ltd.	18221292452	fannieliu@glschina.com	China	6798	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11972	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29845	58
Sangon Biotech (Shanghai) Co.,Ltd.	400-821-026	Sales@sangon.com	China	6813	58
Biosynth Biological Technology (Suzhou) Co Ltd	51288865780	sales@biosynth.com	China	6051	58
Shanghai Amole Biotechnology Co., Ltd.	18916360931 18916360931	2596183085@qq.com	China	17238	58

Posatirelin
N-[(S)-6-Oxo-2-piperidinylcarbonyl]-L-Leu-L-Pro-NH2
RGH-2202
N-[6-Oxopiperidin-2(S)-Ylcarbonyl]-L-Leucyl-L- Prolinamide
BRN 6006446
BRN6006446
BRN-6006446
Posatirelinum
L-Prolinamide, (2S)-6-oxo-2-piperidinecarbonyl-L-leucyl-
78664-73-0

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