Didemnin B
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- CAS-Nr.
- 77327-05-0
- Englisch Name:
- Didemnin B
- Synonyma:
- Didemnin B;Didemnin A, N-[1-[(2S)-2-hydroxy-1-oxopropyl]-L-prolyl]-;N-(L-Lac-L-Pro-N-Methyl-D-Leu-)cyclo[L-Thr*-[(3S,4R)-3-hydroxy-4-[(S)-1-methylpropyl]-γAbu-]-[(2S,4S)-4-hydroxy*-2,5-dimethyl-3-oxohexanoyl]-L-Leu-L-Pro-N,O-dimethyl-L-Tyr-]
- CBNumber:
- CB51247302
- Summenformel:
- C57H89N7O15
- Molgewicht:
- 1112.36
- MOL-Datei:
- 77327-05-0.mol
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Didemnin B Eigenschaften
- Siedepunkt:
- 821.94°C (rough estimate)
- Dichte
- 1.0596 (rough estimate)
- Brechungsindex
- 1.6910 (estimate)
- storage temp.
- Store at -20°C
- L?slichkeit
- Acetonitrile: 1 mg/ml
- Aggregatzustand
- A crystalline solid
- pka
- 11.28±0.70(Predicted)
- Farbe
- White to off-white
- Optische Rotation
- -82.0622 (CHCl3)
- Sequenz
- {(2S)-2-Hydroxypropanoyl-Pro}-{d-N-Me-Leu}-Thr-{(3S,4R,5S)-4-amino-3-hydroxy-5-methylheptanoyl-(2S,4S)-4-hydroxy-2,5-dimethyl-3-oxohexanoyl}-Leu-Pro-{Me-Tyr(Me)} (Lactone: Thr3-Thr8)
- InChIKey
- KYHUYMLIVQFXRI-ZXUAQBDUNA-N
Didemnin B Chemische Eigenschaften,Einsatz,Produktion Methoden
Definition
ChEBI: A natural product found particularly in Lyngbya majuscula and Trididemnum solidum.
in vitro
Didemnin B has activity against miirine B16 melanoma, P388 leukemia, and M5076 sarcoma.
Didemnin B Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Didemnin B Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 52)Lieferanten
- Didemnin B
- N-(L-Lac-L-Pro-N-Methyl-D-Leu-)cyclo[L-Thr*-[(3S,4R)-3-hydroxy-4-[(S)-1-methylpropyl]-γAbu-]-[(2S,4S)-4-hydroxy*-2,5-dimethyl-3-oxohexanoyl]-L-Leu-L-Pro-N,O-dimethyl-L-Tyr-]
- Didemnin A, N-[1-[(2S)-2-hydroxy-1-oxopropyl]-L-prolyl]-
- 77327-05-0
- C57H89N7O15
