2-Methyl-5-nitropyridine
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- CAS-Nr.
- 21203-68-9
- Englisch Name:
- 2-Methyl-5-nitropyridine
- Synonyma:
- AURORA KA-6797;5-NITRO-2-PICOLINE;2-Methyl-5-nitropyri;2-METHYL-5-NITROPYRIDINE;5-Nitro-2-methylpyridine;2-Methy1-5-nitropyridine;Pyridine, 2-methyl-5-nitro-;2-Methyl-5-nitropyridine>2-Methyl-5-nitropyridine 95%;2-METHYL-5-NITROPYRIDINE, 95+%
- CBNumber:
- CB5130896
- Summenformel:
- C6H6N2O2
- Molgewicht:
- 138.12
- MOL-Datei:
- 21203-68-9.mol
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2-Methyl-5-nitropyridine Eigenschaften
- Schmelzpunkt:
- 112 C
- Siedepunkt:
- 237.1±20.0 °C(Predicted)
- Dichte
- 1.246±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 1.92±0.10(Predicted)
- Aggregatzustand
- Solid
- Farbe
- Light yellow to Brown
- Wasserl?slichkeit
- Slightly soluble in water.
- InChI
- InChI=1S/C6H6N2O2/c1-5-2-3-6(4-7-5)8(9)10/h2-4H,1H3
- InChIKey
- USZINSZJSVMICC-UHFFFAOYSA-N
- SMILES
- C1(C)=NC=C([N+]([O-])=O)C=C1
- CAS Datenbank
- 21203-68-9(CAS DataBase Reference)
2-Methyl-5-nitropyridine Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Verwenden
2-Methyl-5-nitropyridine is used as pharmaceutical intermediate.
Synthese
2-(5-nitro-pyridin-2-yl)-malonic acid diethyl ester could be used as a starting material to synthesize 2-methyl-5-nitropyridine. The specific operations are as follows: To 2-(5-nitro-pyridin-2-yl)-malonic acid diethyl ester (12.0 g, 42.5 mmol) was added cold aq. 20% sulfuric acid (120 mL) and the mixture was heated to 100 ℃ for 2h. The cooled reaction was added to a cold dilute sodium hydroxide solution and the pH adjusted to 10. The organics were extracted with dichloromethane (x 4), and then the combined organic phases were dried over sodium sulfate. The filtrate was concentrated to afford 2-methyl-5-nitropyridine (5.0 g, 83 %) as a brown solid.
2-Methyl-5-nitropyridine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-Methyl-5-nitropyridine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 322)Lieferanten
21203-68-9()Verwandte Suche:
- Pyridine, 2-methyl-5-nitro- (9CI)
- 2-METHYL-5-NITROPYRIDINE
- 5-NITRO-2-PICOLINE
- AURORA KA-6797
- 2-METHYL-5-NITROPYRIDINE, 95+%
- 2-METHYL-5-NITROPYRIDINE/5-NITRO-2-PICOLINE
- 2-Methyl-5-nitropyridine Hydrochloride
- 21203-68-9 2-Methyl-5-nitropyridine
- Pyridine, 2-methyl-5-nitro-
- 2-Methyl-5-nitropyri
- 2-Methyl-5-nitropyridine 95%
- 2-Methyl-5-nitropyridine ISO 9001：2015 REACH
- 2-Methyl-5-nitropyridine>
- 5-Nitro-2-methylpyridine
- 2-Methy1-5-nitropyridine
- 21203-68-9
- blocks
- Pyridine
- Pyridines, Pyrimidines, Purines and Pteredines
- NITRO
- pyridines
