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dendrobine

dendrobine Struktur
2115-91-5
CAS-Nr.
2115-91-5
Englisch Name:
dendrobine
Synonyma:
dendrobine;Dendrobine 1%;(-)-Dendrobine;Dendrobine 20%;12-Oxodendrobane;Dendroban-12-one;Dendrobine 2115-91-5;Dendrobine (Standard);From Dendrobium nobile;Dendrobine, 10 mM in DMSO
CBNumber:
CB51331533
Summenformel:
C16H25NO2
Molgewicht:
263.38
MOL-Datei:
2115-91-5.mol

dendrobine Eigenschaften

Schmelzpunkt:
135-136℃
Siedepunkt:
375℃
Dichte
1.101
Flammpunkt:
133℃
storage temp. 
4°C, protect from light
L?slichkeit
≥60mg/ml in MeOH
Aggregatzustand
Powder
pka
9.49±0.60(Predicted)
Farbe
White to yellow
InChI
InChI=1S/C16H25NO2/c1-8(2)11-12-10-6-5-9-7-17(4)14(16(9,10)3)13(11)19-15(12)18/h8-14H,5-7H2,1-4H3/t9-,10+,11+,12-,13-,14-,16+/m1/s1
InChIKey
RYAHJFGVOCZDEI-UFFNCVEVSA-N
SMILES
N1(C)[C@@]2([H])[C@]3(C)[C@@]([H])(CC[C@]3([H])C1)[C@@]1([H])C(=O)O[C@]2([H])[C@H]1C(C)C

Sicherheit

HS Code  29399990

dendrobine Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Dendrobine is a sesquiterpenoid that has been found in D. nobile and has anticancer activity. It decreases viability of A549 cells when used at concentrations ranging from 2.5 to 15 μg/ml. It induces apoptosis in A549 cells when used at concentrations ranging from 1 to 10 μg/ml, as well as increases JNK phosphorylation and sensitizes A549 cells to cisplatin at 10 μg/ml. Dendrobine (50 mg/kg per day) reduces tumor growth in an A549 mouse xenograft model with an additive effect when used in combination with cisplatin.

Verwenden

Dendrobine is an alkaloid isolated from Dendrobium nobile and is an antagonist of β-alanine, taurine and of presynaptic inhibition in the frog spinal cord.

dendrobine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


dendrobine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 221)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21586 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29812 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083
scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897
sales@biopurify.com China 4616 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8615060885618
sales@amoychem.com China 6366 58
NanJing Spring & Autumn Biological Engineering CO., LTD.
+8613815430202
sale02@cqherb.com CHINA 376 58
Shanghai Standard Technology Co., Ltd.
18502101150
ft-sales@nature-standard.com CHINA 1923 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879
sales@chemnorm.com CHINA 2935 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32467 58

2115-91-5()Verwandte Suche:


  • (3α,6α,7R,8S,9R,10α,11α)-Dendrobane-12-one
  • Dendroban-12-one
  • 12-Oxodendrobane
  • 7,5-(EpoxyMethano)-1H-cyclopent[cd]indol-9-one,decahydro-1,7b-diMethyl-6-(1-Methylethyl)-, (2aS,4aS,5R,6S,7R,7aS,7bR)-
  • Dendrobine Dendroban-12-one
  • Dendrobine 1%
  • Dendrobine, 98%, from Dendrobium nobile Lindl
  • Dendrobine 2115-91-5
  • From Dendrobium nobile
  • (-)-Dendrobine
  • (2aS,2a1R,4aS,5R,8R,8aS,9S)-9-isopropyl-1,2a1-dimethyloctahydro-1H-7-oxa-1-aza-5,8-methanocyclopenta[cd]azulen-6(2a1H)-one
  • (2aS,2a1R,4aS,5R,8R,8aS,9S)-9-Isopropyl-2a1,4-dimethyldecahydro-7H-6-oxa-4-aza-5,8-methanocyclopenta[cd]azulen-7-one
  • Dendrobine, 10 mM in DMSO
  • Dendrobine 20%
  • dendrobine
  • Dendrobium oficinale extract
  • Dendrobine (Standard)
  • 2115-91-5
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
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