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Mozavaptan

Mozavaptan Struktur
137975-06-5
CAS-Nr.
137975-06-5
Englisch Name:
Mozavaptan
Synonyma:
CS-134;OPC31260l;OPC 31260;MOZAVAPTAN;Mozavaptan USP/EP/BP;Mozavaptan (OPC-31260);N-(4-(5-(Dimethylamino);Mozavaptan, 10 mM in DMSO;OPC-31260; OPC31260L; OPC 31260;-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)
CBNumber:
CB51388577
Summenformel:
C27H29N3O2
Molgewicht:
427.54
MOL-Datei:
137975-06-5.mol

Mozavaptan Eigenschaften

Schmelzpunkt:
213 - 217°C
Siedepunkt:
543.0±50.0 °C(Predicted)
Dichte
1.21±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
L?slichkeit
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
13.04±0.70(Predicted)
Farbe
White to Off-White
InChIKey
WRNXUQJJCIZICJ-UHFFFAOYSA-N
SMILES
C(NC1=CC=C(C(N2C3=CC=CC=C3C(N(C)C)CCC2)=O)C=C1)(=O)C1=CC=CC=C1C

Sicherheit

Mozavaptan Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Mozavaptan is an oral vasopressin V2 antagonist that has been launched in Japan for inappropriate antidiuretic hormone secretion syndrome (IADHS), an affliction manifesting as hyponatremia. It joins another nonpeptidic benzazepine, conivaptan, which corrects sodium and water imbalance by blocking the renal V2 receptor resulting in enhanced diuresis, thereby effectively increasing serum sodium concentration. While conivaptan inhibits both V1 and V2 receptors, mozavaptan is significantly more selective for V2 (IC50 of 14nM vs. 1.2 mM for V1).

Verwenden

Mozavaptan is a vasopressin-receptor antagonist. It is used in the treatment of congestive heart failure and hyponatremia.

Mozavaptan Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Mozavaptan Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 143)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055
Sibel@chuanghaibio.com China 8738 58
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29812 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8615060885618
sales@amoychem.com China 6366 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49979 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780
sale@simagchem.com China 17346 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226
sales@hzclap.com CHINA 6312 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 28760 58
AFINE CHEMICALS LIMITED
+86-571-85134551
info@afinechem.com China 15081 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471;
sales@sarms4muscle.com China 10473 58
InvivoChem
+1-708-310-1919 +1-13798911105
sales@invivochem.cn United States 6391 58

137975-06-5()Verwandte Suche:


  • OPC 31260
  • MOZAVAPTAN
  • 5-(Dimethylamino)-1-[4-(2-methylbenzamido)benzoyl]-2,3,4,5-tetrahydro-1H-benzazepine
  • Benzamide, N-[4-[[5-(dimethylamino)-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl]phenyl]-2-methyl-
  • -2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)
  • N-(4-(5-(Dimethylamino)
  • CS-134
  • OPC-31260; OPC31260L; OPC 31260
  • OPC31260l
  • N-[4-[[5-(dimethylamino)-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl]phenyl]-2-methyl-
  • Mozavaptan USP/EP/BP
  • N-[4-[5-(dimethylamino)-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]phenyl]-2-methylbenzamide
  • N-(4-(5-(Dimethylamino)-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-2-methylbenzamide
  • Mozavaptan (OPC-31260)
  • Mozavaptan, 10 mM in DMSO
  • 137975-06-5
  • Inhibitors
  • Pharmaceutical intermediate
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