LOCHNERINE Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
This carboline alkaloid has been obtained from Lochnera rosea and is also present
in curare (Strychnos toxifera). Early preparations have been designated Alkaloid
'C' and C-Alkaloid T. It has [α]
D + 56° (pyridine) or + n° (EtOH) and forms a
crystalline picrate with a double melting point of 177-9°C and 243-5°C (dec.).
The methiodide is identical with lochneram iodide, m.p. 235-8°C. A characteristic p-toluenesulphonyl derivative has been prepared, m.p. 153-4°C. One
primary alcoholic hydroxyl is present and the alkaloid yields the O-acetate as
colourless needles, m.p. 243°C; [α]
D - 5.6° ± 3.0° (c 0.36, pyridine). The structure is that of O-methylsarpagine.
Einzelnachweise
Janot, LeMen., Cornpt. rend., 243, 1789 (1956)
Mors et at., Chern. Ind., 173 (1956)
Arnold et at., Helv. Chirn. Acta, 40, 705 (1957)
Arnold et al., ibid, 41, 1505 (1958)
Karrer et at., Angew. Chern., 70,644 (1958)
LOCHNERINE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
