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Propyphenazon

Propyphenazone Struktur
479-92-5
CAS-Nr.
479-92-5
Bezeichnung:
Propyphenazon
Englisch Name:
Propyphenazone
Synonyma:
ISOPROPYLANTIPYRINE;Propyphenazon;(-)-Asparagine;ISOPROPYLPHENAZONE;4-ISOPROPYLANTIPYRINE;Budirol;Causyth;Larodon;Cibalgina;Isopyrine
CBNumber:
CB5193729
Summenformel:
C14H18N2O
Molgewicht:
230.31
MOL-Datei:
479-92-5.mol

Propyphenazon Eigenschaften

Schmelzpunkt:
102-105°C
Siedepunkt:
372.3°C (rough estimate)
Dichte
1.0371 (rough estimate)
Brechungsindex
1.5500 (estimate)
storage temp. 
Sealed in dry,Room Temperature
L?slichkeit
Slightly soluble in water, freely soluble in ethanol (96 per cent) and in methylene chloride.
Aggregatzustand
Solid
pka
1.46±0.65(Predicted)
Farbe
White to Off-White
Wasserl?slichkeit
743.6g/L(25.35 ºC)
Merck 
14,7871
BRN 
204533
Stabilit?t:
Stable. Incompatible with strong oxidizing agents.
CAS Datenbank
479-92-5(CAS DataBase Reference)
NIST chemische Informationen
Propyphenazone(479-92-5)
EPA chemische Informationen
3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl- (479-92-5)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn
R-S?tze: 36/37/38-22
S-S?tze: 26-36/37/39
WGK Germany  3
RTECS-Nr. CD2800000
TSCA  TSCA listed
HS Code  2933.39.9200
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Propyphenazon Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Beschreibung

This uncharacterized alkaloid has been described by Hartsen as occurring in Iso_x0002_pyrum thalictroides L. No chemical or physical characteristics are known.

Chemische Eigenschaften

solid

Verwenden

Analgesic; antipyretic; anti-inflammatory.

Definition

ChEBI: A pyrazolone derivative that is antipyrine substituted at C-4 by an isopropyl group.

Weltgesundheitsorganisation (WHO)

Propyphenazone, a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, was introduced in 1951 for the treatment of rheumatic disorders. As it is structurally related to aminophenazone it has been associated with severe blood dyscrasias. However, it cannot be transformed into potentially carcinogenic nitrosamines and has therefore been widely used as a replacement drug for aminophenazone. In certain countries, products containing propyphenazone have now been restricted in their indications, whereas in others they are still available, sometimes as over-the-counter preparations. See also WHO comment for aminophenazone.

Einzelnachweise

Hartsen., J. Chem. Soc., 511 (1873) Mirande., Compt. rend., 168,316 (1919)

Propyphenazon Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Propyphenazon Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 253)Lieferanten
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+86-0551-65418671 +8618949823763
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AFINE CHEMICALS LIMITED
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Wuhan Fortuna Chemical Co., Ltd
+86-27-59207850
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479-92-5(Propyphenazon)Verwandte Suche:


  • 2,3-dimethyl-4-isopropyl-1-phenyl-3-pyrazolin-5-on
  • 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-
  • 3H-Pyrazol-3-one,1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-
  • 3-Pyrazolin-5-one, 2,3-dimethyl-4-isopropyl-1-phenyl-
  • 4-ISOPROPYL-2,3-DIMETHYL-1-PHENYL-5-PYRAZOLONE
  • 2,3-Dimethyl-1-phenyl-4-isopropylpyrazolone
  • 4-Isopropyl-2,3-dimethyl-1-phenyl-3-pyrazoline-5-on
  • 4-ISO-PROPYL-2,3-DIMETHYL-1-PHENYL-3-PYRAZOLIN-5-ONE(PROPYPHENAZONE)
  • 3,3-Dimethyl-2-Methylene Norcamphone
  • 1,5-Dimethyl-4-(1-methylethyl)-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
  • 1,5-dimethyl-2-phenyl-4-propan-2-yl-pyrazol-3-one
  • 1,5-dimethyl-2-phenyl-4-propan-2-ylpyrazol-3-one
  • 4-isopropyl-1,5-dimethyl-2-phenyl-pyrazol-3-one
  • PROPYLPHENAZONE
  • ANTIBIOTICTPJ-B
  • Propyphenazone (EDMF)
  • 1,2-Dihydro-4-isopropyl-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one
  • 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3h-pyrazol-3-on
  • 3-Pyrazolin-5-one, 4-isopropyl-2,3-dimethyl-1-phenyl-
  • 4-Isopropyl-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
  • 4-isopropyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-on
  • 4-Isopropyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one
  • 4-Isopropyl-2,3-dimethyl-5-oxo-1-phenyl-3-pyrazoline
  • 4-isopropyl-antipyrin
  • 4-Isopropylphenazone
  • Antipyrine, 4-isopropyl-
  • Budirol
  • Causyth
  • Cibalgina
  • Isopropchin
  • Isopropylantipyrin
  • Isopropyrine
  • Isopyrine
  • Larodon
  • ISOPROPYLANTIPYRINUM
  • 4-ISOPROPYL-1,5-DIMETHYL-2-PHENYL-3-PYRAZOLONE
  • PROPYPHENAZONE
  • 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3H-Pyrazol-3-one
  • 1,2-dihydro-1,5-dimethyl-4-(isopropyl)-2-phenyl-pyrazol-3-one
  • 1-Phenyl-2,3-dimethyl-4-isopropyl-3-pyrazolin-5-one
  • 1-phenyl-2,3-dimethyl-4-isopropyl-5-Pyrazolone
  • 1-Phenyl-2,3-dimethyl-4-isopropylpyrazol-5-one
  • 2,3-Dimethyl-4-isopropyl-1-phenyl-3H-pyrazolin-5-one
  • Phentermine Solution, 100ppm
  • 2-propyl-2H-phenazin-1-one
  • Propyphenazone (4-Isopropylantipyrine)
  • 4-Isopropylantipyrine>
  • Propyphenazone CRS
  • 4-isopropyl-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one
  • Propyphenazone USP/EP/BP
  • Propyphenazone, Pharma
  • Isopropyl PhenazoneQ: What is Isopropyl Phenazone Q: What is the CAS Number of Isopropyl Phenazone Q: What is the storage condition of Isopropyl Phenazone
  • Resveratrol Impurity 39(Oxyresveratrol 3'-O-β-D-glucopyranoside)
  • Propyphenazone IP/EP/BP
  • Propyphenazone in methanol
  • C16535000 Propyphenazone
  • Prophenazine
  • Propyphenazone, 10 mM in DMSO
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