Anti-sir2-like 4, Anti-SIR2L4, Anti-sirtuin 4, Anti-sirtuin type 4, Anti-Sirtuin (silent mating type information regulation 2 homolog) 4 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-SIRT4 has been used in immunohistochemistry.
Allgemeine Beschreibung
SIRT4 (sirtuin 4) belongs to sirtuin family of nicotinamide adenine dinucleotide-dependent enzymes. It is a NAD
+-dependent ADP ribosyltransferase, that is located in the mitochondria. SIRT4 protein level is found to be more in ESCC (esophageal squamous cell carcinoma) tissues.
Biochem/physiol Actions
SIRT4 (sirtuin 4) may involve in the development of esophageal cancer. Growth of HeLa cells can be suppressed by the overexpression of SIRT4. It modulates glutamine metabolism and may also act as a tumor suppressor. It plays some important roles in multiple cellular processes like stress response and longevity. It may act as an important therapeutic target in colorectal cancer.
Anti-sir2-like 4, Anti-SIR2L4, Anti-sirtuin 4, Anti-sirtuin type 4, Anti-Sirtuin (silent mating type information regulation 2 homolog) 4 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
