ANTI-FKHRL1 (FOXO3A) RABBIT Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anti-FKHRL1 (FOXO3a) antibody produced in rabbit has been used in:

• immunohistochemistry
• western blotting
• immunofluorescence staining

Allgemeine Beschreibung

Forkhead family transcription factor (FKHRL1), also known as FOX3a, is a member of the forkhead transcription factor superfamily. In FKHRL1 (FOX3a), there are three PKB phosphorylation consensus sites, Thr³², Ser²⁵³, and Ser³¹⁵. Thr³² and Ser²⁵³ are phosphorylated by PKB after induction by survival factors such as IGF-1.

Biochem/physiol Actions

Forkhead transcription factor superfamily proteins act as the targets of the phosphoinositide-3-kinase–protein kinase B/Akt (PI3K-PKB) pathway. FKHRL1/FOXO3a modulates the expression of several genes that regulate DNA repair in response to stress at the G2-M checkpoint and aging. Other genes that are regulated by FKHRL1 include mitotic genes such as cyclin B and polo-like kinase (plk). Antibodies reacting specifically with FKHRL1 (FOXO3) may be useful in studying the expression and function of the protein, as well as for correlating their expression pattern with physiological functions or pathological conditions.

ANTI-FKHRL1 (FOXO3A) RABBIT Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ANTI-FKHRL1 (FOXO3A) RABBIT Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Merck KGaA	--	ordercn@merckgroup.com	China	6376	58

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• Monoclonal Anti-FKHRL1 (FOXO3a) antibody produced in mouse
• Anti-FKHRL1 (FOXO3a) antibody produced in rabbit
• ANTI-FKHRL1 (FOXO3A) RABBIT
• MONOCLONAL ANTI-FKHRL1 (FOXO3A)
• FCancer Research
• PI3K-Akt-mTOR Transcription Factors
• Tumor Growth Regulation
• Alphabetical Index
• Antibodies for Gene Regulation and Expression
• Antibodies to Transcription FactorsAntibodies
• Cell Biology
• Clone Index
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• FAntibodies