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ANTI-HUMAN IGG4

ANTI-HUMAN IGG4 Struktur
CAS-Nr.
Englisch Name:
ANTI-HUMAN IGG4
Synonyma:
ANTI-HUMAN IGG4;ANTI-IGG4, HUMAN;ANTI-IMMUNOGLOBULIN G4, HUMAN;ANTI-HUMAN IGG4 (PFC' SPECIFIC);ANTI-IMMUNOGLOBULIN G (SUBCLASS 4);ANTI-HUMAN IGG SUBCLASS 4 ISOTYPE: IGG3;Monoclonal Anti-Human IgG4 antibody produced in mouse;Monoclonal Anti-Human IgG4 (pFcμ specific) antibody produced in mouse
CBNumber:
CB5222694
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ANTI-HUMAN IGG4 Eigenschaften

storage temp. 
-20°C
Biologische Quelle
mouse

Sicherheit

Kennzeichnung gef?hrlicher Xn
R-S?tze: 21/22
S-S?tze: 36/37
WGK Germany  3
Speicherklasse 10 - Combustible liquids

ANTI-HUMAN IGG4 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

The IUIS/WHO2 study singled out this monoclonal antibody as one of the most widely applicable IgG4 specific monoclonal antibodies. Monoclonal Anti-Human IgG4 may be used for the identification of the IgG4 subclass by various immunoassays including: ELISA, Imprint Immunofixation (IIF), Immunofluorometric Assay (IFMA), Hemagglutination (HA), Hemagglutination Inhibition (HAI), Particle Counting Immunoassay (PACIA), and detection of cytoplasmic IgG.

Allgemeine Beschreibung

IgG4 (Immunoglobulin G4) is produced by T helper 2 cytokines. Unlike other immunoglobulin G is rare and constitutes to only 3-4 percent of the total IgG in the serum.

Biochem/physiol Actions

IgG4 (Immunoglobulin G4) antibody has reduced affinity for C1q (first component of complement q) and hence its anti-inflammatory activity differing from that of the other IgG subclasses. IgG4 antibodies are known to actively interchange Fab arms with another molecule, resulting in recombined antibodies with two different binding specificities. This exchange is considered as an important biological mechanism that contributes to its anti-inflammatory activity. IgG4 antibodies are normally noninflammatory, but autoreactive IgG4 antibodies are known to be associated with Immunoglobulin G4 (IgG4)-related disease (IgG4-RD), characterized by infiltrating lymphoplasmacytic cells and elevated serum IgG4. Increased levels of IgG4 is observed in atopic dermatitis, parasitic diseases, pemphigus vulgaris and pemphigus foliaceus.

ANTI-HUMAN IGG4 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-HUMAN IGG4 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 14)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Merck KGaA --
ordercn@merckgroup.com China 6394 58

  • Monoclonal Anti-Human IgG4 antibody produced in mouse
  • Monoclonal Anti-Human IgG4 (pFcμ specific) antibody produced in mouse
  • ANTI-HUMAN IGG4
  • ANTI-HUMAN IGG SUBCLASS 4 ISOTYPE: IGG3
  • ANTI-HUMAN IGG4 (PFC' SPECIFIC)
  • ANTI-IGG4, HUMAN
  • ANTI-IMMUNOGLOBULIN G4, HUMAN
  • ANTI-IMMUNOGLOBULIN G (SUBCLASS 4)
  • Unconjugated
  • Alphabetical Index
  • Antibodies
  • by Animal
  • by Label
  • Clone Index
  • HSecondary Antibodies
  • HAntibodies
  • Human IgG Secondary Antibodies and ConjugatesSecondary Antibodies
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