(R)-SLV 319

656827-86-0

CAS-Nr.: 656827-86-0

Englisch Name:: (R)-SLV 319

Synonyma:: (R)-SLV 319;SLV 319, (R)-(+)-;(4R)-5-(4-chlorophenyl)-N-(4-chlorophenyl)sulfonyl-N'-methyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide;4-chloro-N-{[3-(4-chloro-phenyl)-4-phenyl-4,5-dihydro-pyrazol-1-yl]-methylamino-methylene}-benzenesulfonamide;(4R)-3-(4-Chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N'-methyl-4-phenyl-1H-pyrazole-1-carboximidamide;1H-Pyrazole-1-carboximidamide, 3-(4-chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N'-methyl-4-phenyl-, (4R)-

CBNumber:: CB52453032

Summenformel:: C23H20Cl2N4O2S

Molgewicht:: 487.4

MOL-Datei:: 656827-86-0.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 34

(R)-SLV 319 Eigenschaften

Siedepunkt:: 623.2±65.0 °C(Predicted)

Dichte: 1.38±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

L?slichkeit: ≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide

Aggregatzustand: crystalline solid

pka: 11+-.0.60(Predicted)

Sicherheit

(R)-SLV 319 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Central cannabinoid (CB₁) receptor antagonists may have potential in the treatment of a number of diseases such as neuroinflammatory disorders, cognitive disorders, septic shock, obesity, psychosis, addiction, and gastrointestinal disorders. (R)-SLV 319 is the inactive enantiomer of SLV 319 with 100-fold less affinity for the CB₁ receptor. SLV 319 is a potent and selective CB₁ receptor antagonist with K_i values of 7.8 and 7,943 nM for CB₁ and peripheral cannabinoid (CB₂) receptors, respectively. SLV 319 is less lipophilic (log P = 5.1) and therefore more water soluble than other known CB₁ receptor ligands.

(R)-SLV 319 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(R)-SLV 319 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 34)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9804	58
BOC Sciences	--	info@bocsci.com	USA	0	65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
TargetMol Chemicals Inc.	4008200310 15002144251	marketing@tsbiochem.com	China	24959	58
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd	18162595016; 18162595016	3287908757@qq.com	China	9119	58
Cayman Chemical Company	--	sales@caymanchem.com	China	6838	58
Biosynth Biological Technology (Suzhou) Co Ltd	--	sales@biosynth.com	China	6051	58
ApexBio Technology	--	sales@apexbt.com	United States	6251	58

(R)-SLV 319
(4R)-5-(4-chlorophenyl)-N-(4-chlorophenyl)sulfonyl-N'-methyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
4-chloro-N-{[3-(4-chloro-phenyl)-4-phenyl-4,5-dihydro-pyrazol-1-yl]-methylamino-methylene}-benzenesulfonamide
1H-Pyrazole-1-carboximidamide, 3-(4-chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N'-methyl-4-phenyl-, (4R)-
SLV 319, (R)-(+)-
(4R)-3-(4-Chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N'-methyl-4-phenyl-1H-pyrazole-1-carboximidamide
656827-86-0

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