2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
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- CAS-Nr.
- 890842-28-1
- Englisch Name:
- 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
- Synonyma:
- GSK 650394;CS-1142;GSK650394 ,S7209;GSK650394 (Free base);SGK inhibitor GS650394;GSK 650394, 10 mM in DMSO;6-O-α-D-Glucopyranosyl-D-glucose;2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid;Benzoic acid, 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-
- CBNumber:
- CB52518968
- Summenformel:
- C25H22N2O2
- Molgewicht:
- 382.45
- MOL-Datei:
- 890842-28-1.mol
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2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Eigenschaften
- storage temp.
- room temp
- L?slichkeit
- DMSO: soluble20mg/mL, clear
- Aggregatzustand
- powder
- Farbe
- white to beige
- InChI
- 1S/C25H22N2O2/c28-25(29)20-11-10-18(12-21(20)17-8-4-5-9-17)23-15-27-24-22(23)13-19(14-26-24)16-6-2-1-3-7-16/h1-3,6-7,10-15,17H,4-5,8-9H2,(H,26,27)(H,28,29)
- InChIKey
- WVSBGSNVCDAMCF-UHFFFAOYSA-N
- SMILES
- [nH]1c2ncc(cc2c(c1)c4cc(c(cc4)C(=O)O)C5CCCC5)c3ccccc3
Sicherheit
| WGK Germany |
3 |
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| Speicherklasse |
11 - Combustible Solids |
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2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
GSK-650394 has been used as a serum and glucocorticoid-activated kinase (SGK1) inhibitor.
Biochem/physiol Actions
GSK-650394 has an IC50 value of 62nM for serum and glucocorticoid-activated kinase-1 (SGK1) and 103nM for SGK2. It has an ability to stop viral replication at concentrations that are nontoxic to cells.
2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 129)Lieferanten
890842-28-1()Verwandte Suche:
- GSK650394 (Free base)
- 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
- SGK inhibitor GS650394
- CS-1142
- Benzoic acid, 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-
- 6-O-α-D-Glucopyranosyl-D-glucose
- GSK 650394, 10 mM in DMSO
- GSK650394 ,S7209
- GSK 650394
- 890842-28-1
- Inhibitors