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2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid

2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Struktur
890842-28-1
CAS-Nr.
890842-28-1
Englisch Name:
2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
Synonyma:
GSK 650394;CS-1142;GSK650394 ,S7209;GSK650394 (Free base);SGK inhibitor GS650394;GSK 650394, 10 mM in DMSO;6-O-α-D-Glucopyranosyl-D-glucose;2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid;Benzoic acid, 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-
CBNumber:
CB52518968
Summenformel:
C25H22N2O2
Molgewicht:
382.45
MOL-Datei:
890842-28-1.mol

2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Eigenschaften

storage temp. 
room temp
L?slichkeit
DMSO: soluble20mg/mL, clear
Aggregatzustand
powder
Farbe
white to beige
InChI
1S/C25H22N2O2/c28-25(29)20-11-10-18(12-21(20)17-8-4-5-9-17)23-15-27-24-22(23)13-19(14-26-24)16-6-2-1-3-7-16/h1-3,6-7,10-15,17H,4-5,8-9H2,(H,26,27)(H,28,29)
InChIKey
WVSBGSNVCDAMCF-UHFFFAOYSA-N
SMILES
[nH]1c2ncc(cc2c(c1)c4cc(c(cc4)C(=O)O)C5CCCC5)c3ccccc3

Sicherheit

WGK Germany  3
Speicherklasse 11 - Combustible Solids

2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

GSK-650394 has been used as a serum and glucocorticoid-activated kinase (SGK1) inhibitor.

Biochem/physiol Actions

GSK-650394 has an IC50 value of 62nM for serum and glucocorticoid-activated kinase-1 (SGK1) and 103nM for SGK2. It has an ability to stop viral replication at concentrations that are nontoxic to cells.

2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 129)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 33024 60
Biochempartner
0086-13720134139
candy@biochempartner.com CHINA 965 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32467 58
InvivoChem
+1-708-310-1919 +1-13798911105
sales@invivochem.cn United States 6391 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207
sales@molcore.com China 49734 58
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581
sales@chemhifuture.com China 3135 58
Aladdin Scientific

tp@aladdinsci.com United States 57505 58
Wuhan Jingkang en Biomedical Technology Co., Ltd
+8613720134139
orders@jknbiochem.com China 5221 58
Amadis Chemical Company Limited
571-89925085
sales@amadischem.com China 131956 58
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037
3bsc@sina.com China 15838 69

890842-28-1()Verwandte Suche:


  • GSK650394 (Free base)
  • 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
  • SGK inhibitor GS650394
  • CS-1142
  • Benzoic acid, 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-
  • 6-O-α-D-Glucopyranosyl-D-glucose
  • GSK 650394, 10 mM in DMSO
  • GSK650394 ,S7209
  • GSK 650394
  • 890842-28-1
  • Inhibitors
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