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FC 131

FC 131 Struktur
606968-52-9
CAS-Nr.
606968-52-9
Englisch Name:
FC 131
Synonyma:
FC131,FC-131;cyclo(2Nal-Gly-D-Tyr-Arg-Arg);FC 131, CXCR4 activation inhibitor;Cyclo[3-(2-naphthalenyl)-L-alanylglycyl-D-tyrosyl-L-arginyl-L-arginyl]
CBNumber:
CB52550797
Summenformel:
C36H47N11O6
Molgewicht:
729.83
MOL-Datei:
606968-52-9.mol

FC 131 Eigenschaften

Dichte
1.45±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 1 mg/ml
pka
9.89±0.15(Predicted)
Aggregatzustand
Powder
Wasserl?slichkeit
Soluble to 2 mg/ml in water

Sicherheit

FC 131 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

C-X-C chemokine receptor 4 (CXCR4) is a receptor for the stromal cell-derived factor-1 (SDF-1) which is designated as chemokine ligand 12 (CXCL12). It is involved in cell progression, hematopoiesis, cancer, HIV entry, and rheumatoid arthritis. FC 131 is an inhibitor of CXCR4 activation by SDF-1 (IC50 = 4.5 nM) and also blocks HIV-induced cytopathogenicity (EC50 = 73 nM). FC 131 derivatives can be used for imaging CXCR4 and elucidating its function.

Verwenden

Cyclo[3-(2-naphthalenyl)-L-alanylglycyl-D-tyrosyl-L-arginyl-L-arginyl] is a CXCR4 antagonist with anti-HIV properties.

FC 131 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


FC 131 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 38)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32466 58
BOC Sciences
16314854226; +16314854226
inquiry@bocsci.com United States 19853 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471;
sales@sarms4muscle.com China 10473 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850
market18@leapchem.com China 43333 58
Aladdin Scientific

tp@aladdinsci.com United States 52923 58
Changsha MOL Changes Biotechnology Co., Ltd.
+8619375158599
info@molchanges.com China 5218 58
VDM Biochemicals 0330-2528181
sales@vdmbio.com United States 510 64
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632
sales@reading-chemicals.com China 15178 58
Creative Peptides
info@creative-peptides.com United States 6083 56
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9804 58

  • Cyclo[3-(2-naphthalenyl)-L-alanylglycyl-D-tyrosyl-L-arginyl-L-arginyl]
  • FC131,FC-131
  • cyclo(2Nal-Gly-D-Tyr-Arg-Arg)
  • FC 131, CXCR4 activation inhibitor
  • 606968-52-9
  • C36H47N11O6
  • C36H47N11O6free
  • CXCR4 antagonist.
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