Octanoic acid, 6,8-bis[(phenylMethyl)thio]-
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- CAS-Nr.
- 95809-78-2
- Englisch Name:
- Octanoic acid, 6,8-bis[(phenylMethyl)thio]-
- Synonyma:
- Devimistat;CPI-613;6,8-Bis(benzylsulfanyl)octanoic acid;Devimista;CPI-613, >98%;CPI 613;CPI613;CPI-613(Devimistat);Devimistat (CPI-613);CPI-613;CPI 613;CPI613;Devimistat, 10 mM in DMSO
- CBNumber:
- CB52554078
- Summenformel:
- C22H28O2S2
- Molgewicht:
- 388.59
- MOL-Datei:
- 95809-78-2.mol
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Octanoic acid, 6,8-bis[(phenylMethyl)thio]- Eigenschaften
- Schmelzpunkt:
- 63-65℃
- Siedepunkt:
- 553.0±50.0 °C(Predicted)
- Dichte
- 1.149
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO: soluble15mg/mL (clear solution)
- Aggregatzustand
- powder
- pka
- 4.75±0.10(Predicted)
- Farbe
- white to beige
- Stabilit?t:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
- InChI
- InChI=1S/C22H28O2S2/c23-22(24)14-8-7-13-21(26-18-20-11-5-2-6-12-20)15-16-25-17-19-9-3-1-4-10-19/h1-6,9-12,21H,7-8,13-18H2,(H,23,24)
- InChIKey
- ZYRLHJIMTROTBO-UHFFFAOYSA-N
- SMILES
- C(O)(=O)CCCCC(SCC1=CC=CC=C1)CCSCC1=CC=CC=C1
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
N |
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| R-S?tze: |
50/53 |
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| S-S?tze: |
60-61 |
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| RIDADR |
UN 3077 9 / PGIII |
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| WGK Germany |
3 |
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| HS Code |
2930.90.2900 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Aquatic Acute 1
Aquatic Chronic 1 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H410 |
Sehr giftig für Wasserorganismen mit langfristiger Wirkung. |
Langfristig (chronisch) gew?ssergef?hrdend |
Kategorie 1 |
Warnung |
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P273, P391, P501 |
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| Sicherheit |
| P273 |
Freisetzung in die Umwelt vermeiden. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Octanoic acid, 6,8-bis[(phenylMethyl)thio]- Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
CPI 613 is a class of non-redox-active lipoate derivative that disrupts cancer cell mitochondrial metabolism and are potent anticancer agents in vivo.
Biochem/physiol Actions
6,8-Bis(benzylthio)-octanoic acid (CPI-613) is a lipoate analog. It acts as a mitochondrial disrupter by blocking the mitochondrial enzymes pyruvate dehydrogenase and α-ketoglutarate dehydrogenase.
Octanoic acid, 6,8-bis[(phenylMethyl)thio]- Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Octanoic acid, 6,8-bis[(phenylMethyl)thio]- Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 187)Lieferanten
95809-78-2()Verwandte Suche:
- alpha-lipoic acid analogue CPI-613
- CPI-613; OCTANOIC ACID, 6,8-BIS[(PHENYLMETHYL)THIO]-
- Octanoic acid, 6,8-bis[(phenylMethyl)thio]-
- 6,8-Bis(benzylthio)octanoic acid
- 6,8-Bis[(phenylmethyl)thio]octanoic acid
- 6,8-Bis[(phenylmethyl)thio]octanoic acid CPI-613
- CPI 613;CPI613
- (+/-)6,8-bis-thiobenzyl octanoic acid
- CPI-613(Devimistat)
- CPI-613;CPI 613;CPI613
- CPI-613, >98%
- CPI613; CPI-613; CPI 613; DEVIMISTAT
- Octanoic acid, 6,8-bis[(phenylMethyl)thio]- USP/EP/BP
- Devimistat (CPI-613)
- 6,8-Bis(benzylsulfanyl)octanoicaci
- Devimistat, 10 mM in DMSO
- Devimista
- 6,8-Bis(benzylsulfanyl)octanoic acid
- CPI-613
- Devimistat
- 95809-78-2
- Inhibitor
- Inhibitors
