ANTI-TYROSINE HYDROXYLASE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Monoclonal Anti-Tyrosine Hydroxylase antibody produced in mouse has also been used in

• western blotting
• immunofluorescence labelling
• immunohistochemical staining
• enzyme linked immunosorbent assay (ELISA)
• dot blot
• immunoprecipitation
• immunocytochemistry

Allgemeine Beschreibung

Monoclonal Anti-Tyrosine Hydroxylase (mouse IgG1 isotype) is derived from the TH-16 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from immunized BALB/c mice. Tyrosine hydroxylase (TH) exists in four isoforms in humans. They are are TH-1 (M.W. 55,600), TH-2 (4 additional amino acids; M.W. 56,000), TH-3, (27 additional amino acids; M.W. 58,100), and TH-4 (4 plus 27 additional amino acids; 58,500). Only humans express all four isoforms; all other anthropoids express only the TH-1 and TH-2 isoforms.

Biochem/physiol Actions

Tyrosine hydroxylase (TH) catalyzes the first rate limiting step in the biosynthesis of catecholamine neurotransmitter i.e. the conversion of L-tyrosine to L-dopa. Inhibition of TH by L-phenylalanine, might play a crucial role in phenylketonuria and block the synthesis of norepinephrine. Activity of TH can be regulated by phosphorylation. Decreased expression of TH is associated with various neuropsychiatric diseases such as schizophrenia and Parkinson′s disease (PD).

ANTI-TYROSINE HYDROXYLASE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ANTI-TYROSINE HYDROXYLASE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51395	80
Atlas antibodies	--	order@atlasantibodies.com	China	6586	58
Merck Millipore	--	bioscience@merckgroup.com	China	6839	58
Merck KGaA	--	ordercn@merckgroup.com	China	6394	58
Abmart Inc	--	market@ab-mart.com	China	6917	58
Guangdong Zijinggang Technology Co., Ltd.	--		CHINA	6879	58
Guangzhou Weike Biotechnology Co., Ltd.	--		CHINA	6233	58
Guangzhou Kati Biotechnology Co., Ltd.	--		CHINA	6598	58
Guangzhou Sanxu Biotechnology Co., Ltd.	--		CHINA	6456	58
Guangzhou Kangkaixin Biotechnology Co., Ltd.	--		CHINA	6788	58

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• Anti-Th (Ab-31) antibody produced in rabbit
• Monoclonal Anti-Tyrosine Hydroxylase antibody produced in mouse
• ANTI-RAT TYROSINE HYDROXYLASE
• ANTI-TYROSINE HYDROXYLASE
• ANTI-TYROSINE HYDROXYLASE MOUSE MAB
• ANTI-TYROSINE HYDROXYLASE RABBIT PAB
• ANTI-TYROSINE HYDROXYLASE, RAT
• ANTI-TYROSINE HYDROXYLASE, RAT (MOUSE)
• ANTI-TYROSINE HYDROXYLASE, RAT (RABBIT)
• ANTI-TYROSINE HYDROXYLASE, RAT (SHEEP)
• ANTI-TYROSINE HYDROXYLASE SHEEP PAB
• ANTI-TH
• ANTI-TH, RAT
• Anti-Tyrosine 3-monooxygenase
• Anti-Tyrosine 3-hydroxylase