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27-DEOXYACTEIN

27-DEOXYACTEIN Struktur
264624-38-6
CAS-Nr.
264624-38-6
Englisch Name:
27-DEOXYACTEIN
Synonyma:
23-EPI-26-DEOXYACTEIN;26-DEOXYACTEIN;Deoxycosimatin;27-DEOXYACTEIN;DEOXYACTEIN, 27-;26-Deoxyactein, 10 mM in DMSO;23-EPI-26-Deoxyactein (20 mg);DEOXYACTEIN, 27-(23-EPI-26-DEOXYACTEIN)(P);Inhibitor,26Deoxyactein,26-Deoxyactein,inhibit,26 Deoxyactein;β-D-Xylopyranoside, (3β,12β,16β,23S,24R,25R)-12-(acetyloxy)-16,23:23,26:24,25-triepoxy-9,19-cyclolanostan-3-yl
CBNumber:
CB5365803
Summenformel:
C37H56O10
Molgewicht:
660.83
MOL-Datei:
264624-38-6.mol

27-DEOXYACTEIN Eigenschaften

Schmelzpunkt:
253~254℃
Dichte
1.32±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
L?slichkeit
Chloroform (Slightly), Methanol (Very Slightly), Pyridine (Slightly)
Aggregatzustand
Solid
pka
13.03±0.70(Predicted)
Farbe
White to Off-White
Stabilit?t:
Hygroscopic
Major Application
pharmaceutical (small molecule)
InChIKey
GCMGJWLOGKSUGX-RBKCHLQLSA-N

Sicherheit

WGK Germany  WGK 3
Speicherklasse 11 - Combustible Solids

27-DEOXYACTEIN Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

23-epi-26-Deoxyactein is a triterpene glycoside and a major constituent of black cohosh (C. racemosa). It reduces intracellular calcium concentrations, collapse of the mitochondrial membrane potential, production of reactive oxygen species (ROS), and cardiolipin peroxidation and inhibits autophagy and apoptosis in osteoblastic MC3T3-E1 cells induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). 23-epi-26-Deoxyactein (0.01-10 μM) reduces production of ROS and IL-1β and cell death induced by methylglyoxal in RIN-m5F β-cells.

Verwenden

27-Deoxyactein has shown stimulation of osteoblast function and inhibits bone resorbing mediators in the treatment of osteoporosis. It is a derivative of Actein (A191800), a gamma secretase modulators derived from botanicals.

27-DEOXYACTEIN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


27-DEOXYACTEIN Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 100)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3619 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083
scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897
sales@biopurify.com China 4616 58
Aktin Chemicals, Inc.
028-85159085
info@aktinchem.com CHINA 1025 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850
market18@leapchem.com China 24597 58
TargetMol Chemicals Inc.
+1-781-999-5354;
support@targetmol.com United States 39040 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+86-18621343501; +undefined18621343501
product@acmec-e.com China 33324 58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
+8618791163155
18791163155@163.com China 3397 58
Aladdin Scientific

tp@aladdinsci.com United States 52923 58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580
cooperation@kean-chem.com China 40066 58

264624-38-6()Verwandte Suche:


  • 23-EPI-26-Deoxyactein (20 mg)
  • DEOXYACTEIN, 27-(23-EPI-26-DEOXYACTEIN)(P)
  • (3beta,12beta,16beta,23S,24R,25R)-12-(Acetyloxy)-16,23:23,26:24,25-triepoxy-9,19-cyclolanostan-3-yl beta-D-xylopyranoside
  • DEOXYACTEIN, 27-
  • 27-DEOXYACTEIN
  • β-D-Xylopyranoside, (3β,12β,16β,23S,24R,25R)-12-(acetyloxy)-16,23:23,26:24,25-triepoxy-9,19-cyclolanostan-3-yl
  • Inhibitor,26Deoxyactein,26-Deoxyactein,inhibit,26 Deoxyactein
  • Deoxycosimatin
  • 26-Deoxyactein, 10 mM in DMSO
  • 23-EPI-26-DEOXYACTEIN
  • 26-DEOXYACTEIN
  • 264624-38-6
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