ANTI-INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR (TYPE-I) Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

The gene ITPR1 (inositol 1,4,5-triphosphate receptor type 1) encodes an intracellular receptor that binds to inositol 1,4,5 trisphosphate. It is localized to membranes of endoplasmatic or sarcoplasmatic (in muscle cells) reticulum. The gene is mapped to human chromosome 3p26.

Biochem/physiol Actions

The ligand-gated calcium channel encoded by the gene ITPR1 (inositol 1,4,5-triphosphate receptor type 1) is stimulated upon binding to its ligand inositol 1,4,5-triphosphate, and mediates intracellular calcium signaling. It facilitates the release of Ca2+ from endoplasmic reticulum and modulates intracellular Ca2+ concentration. This is a crucial mechanism in the initial stages of myoblast differentiation. Mutations in this gene have been associated with sporadic infantile-onset cerebellar ataxia.

ANTI-INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR (TYPE-I) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ANTI-INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR (TYPE-I) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Merck KGaA	--	ordercn@merckgroup.com	China	6394	58

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• POLYCLONAL ANTIBODY TO INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR TYPE I
• Anti-Inositol 1,4,5-Triphosphate Receptor (Type I) antibody produced in rabbit
• ANTI-INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR (TYPE-I)
• ANTI-IP3 RECEPTOR (TYPE-I)
• ANTI-INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR (TYPE I)
• ANTI-IP3R-I
• ANTISERUM TO INS(1,4,5)P3, RECEPTOR TYPE I
• IP3 RECEPTOR TYPE I
• Alphabetical Index
• Antibodies to Calcium ChannelsAntibodies
• Antibodies to Ion Channels
• Antibodies to Voltage-Gated Ion Channels
• I