9-Fluor-11β,17-dihydroxy-6α-methylpregna-1,4-dien-3,20-dion-17-acetat
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- CAS-Nr.
- 3801-06-7
- Bezeichnung:
- 9-Fluor-11β,17-dihydroxy-6α-methylpregna-1,4-dien-3,20-dion-17-acetat
- Englisch Name:
- Eflone
- Synonyma:
- fluorometholone acetate;Oxylone Acetate;Flarex;eflone;U 17323;NSC 47438;Nolpitantium;Eflone USP/EP/BP;Flumetholon acetate;Lumacaftor Impurity 6
- CBNumber:
- CB5501395
- Summenformel:
- C24H31FO5
- Molgewicht:
- 418.5
- MOL-Datei:
- 3801-06-7.mol
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9-Fluor-11β,17-dihydroxy-6α-methylpregna-1,4-dien-3,20-dion-17-acetat Eigenschaften
- Schmelzpunkt:
- 230-232°
- alpha
- D +28° (chloroform)
- Siedepunkt:
- 532.1±50.0 °C(Predicted)
- Dichte
- 1.24±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- L?slichkeit
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 13.01±0.70(Predicted)
- Farbe
- Off-White to Light Yellow
- Major Application
- pharmaceutical (small molecule)
- InChIKey
- YRFXGQHBPBMFHW-ZGNMMXMRNA-N
- SMILES
- [C@]12(F)[C@@]([H])(O)C[C@]3(C)[C@](CC[C@@]3([H])[C@]1([H])C[C@]([H])(C)C1=CC(=O)C=C[C@]21C)(C(=O)C)OC(=O)C |&1:0,2,6,8,11,13,16,25,r|
Sicherheit
| WGK Germany |
WGK 3 |
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| HS Code |
2937220000 |
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| Speicherklasse |
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects |
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| Hazard Classifications |
Repr. 1B |
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9-Fluor-11β,17-dihydroxy-6α-methylpregna-1,4-dien-3,20-dion-17-acetat Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Off-White to Pale Yellow Solid
Verwenden
Fluorometholone Acetate is a glucocorticoid; anti-inflammatory.
Definition
ChEBI: A steroid ester resulting from the formal condensation of the 17-hydroxy function of fluorometholone with acetic acid. Used in the treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment
of the eye.
Synthese
The preparation method of the fluorometholone acetate (Eflone) comprises the
following steps: taking a compound shown as a formula II as a raw
material, and sequentially carrying out dechlorination reaction,
esterification reaction, methylation reaction, hydrogenation reaction,
fermentation dehydrogenation reaction, epoxy reaction and ring-opening
reaction to prepare the fluorometholone acetate.
9-Fluor-11β,17-dihydroxy-6α-methylpregna-1,4-dien-3,20-dion-17-acetat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
9-Fluor-11β,17-dihydroxy-6α-methylpregna-1,4-dien-3,20-dion-17-acetat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 185)Lieferanten
3801-06-7(9-Fluor-11β,17-dihydroxy-6α-methylpregna-1,4-dien-3,20-dion-17-acetat)Verwandte Suche:
- FLUOROMETHOLONE ACETATE (200 MG)
- 9-fluoro-11b,17-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione 17-acetate
- eflone
- 9-fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 17-acetate
- Nolpitantium
- FLUROMETHOLONE ACETATE
- 17-(Acetyloxy)-9-fluoro-11β-hydroxy-6α-methylpregna-1,4-diene-3,20-dione
- (6α,11β)-17-(Acetyloxy)-9-fluoro-11-hydroxy-6-Methylpregna-1,4-diene-3,20-dione
- 6α-Methyl-9α-fluoro-17-acetoxy-21-deoxyprednisolone
- NSC 47438
- U 17323
- Pregna-1,4-diene-3,20-dione,17-(acetyloxy)-9-fluoro-11-hydroxy-6-Methyl-, (6a,11b)-
- FluoroMetholone 17- acetate
- Pregna-1,4-diene-3,20-dione, 17-(acetyloxy)-9-fluoro-11-hydroxy-6-methyl-, (6α,11β)-
- Flumetholon acetate
- 9-fluoro-11β,17-dihydroxy-6α-methylpregna-1,4-diene-3,20-dione 17-acetate
- FLUOROMETHALONE ACETATE
- Eflone USP/EP/BP
- Fluorometholone Acetate (1278109)
- Flarex
- Oxylone Acetate
- Eflone / FLUROMETHOLONE ACETATE
- 9-fluoro-11b,17-dihydroxy-6a-methylpregna-1,4-diene-3,20-Chemicalbookdione17-acetate
- 9-fluoro-11β,17-dihydroxy-6α-methylpregna-1,4-diene-3,20-dione17-acetate
- (6S,8S,9R,10S,11S,13S,14S,17R)-17-Acetyl-9-fluoro-11-hydroxy-6,10,13-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl acetate
- (6s,8s,9r,10s,11s,13s,14s,17r)-17-acetyl-9-fluoro-11-hydroxy-6,10,13-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] Acetate
- Lumacaftor Impurity 6
- Fluorometholone Acetate, 10 mM in DMSO
- Fluorometholone Acetate (Standard)
- fluorometholone acetate
- 3801-06-7
- 3801-6-7
- C24H31FO5
- Inhibitors
- Hormone Drugs
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Steroids
