一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Tanshinone IIA

Tanshinone IIA Struktur
568-72-9
CAS-Nr.
568-72-9
Englisch Name:
Tanshinone IIA
Synonyma:
TANSHINONE ⅡA;Tanshinone B;Tanshinone 2A;tanshiones;SweetOrange;Tanshine II;ANSHINONE ⅡA;TanshinoneⅡA;Tanshionesiia;TANSHINONE A
CBNumber:
CB5705548
Summenformel:
C19H18O3
Molgewicht:
294.34
MOL-Datei:
568-72-9.mol

Tanshinone IIA Eigenschaften

Schmelzpunkt:
196.0 to 200.0 °C
Siedepunkt:
480.7±44.0 °C(Predicted)
Dichte
1.209±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
methanol: soluble5mg/mL, clear, red-orange to red
Aggregatzustand
powder, red
Farbe
Orange
Henry's Law Constant
2.0×103 mol/(m3Pa) at 25℃, HSDB (2015)
Stabilit?t:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Major Application
food and beverages
InChI
InChI=1S/C19H18O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,9H,4-5,8H2,1-3H3
InChIKey
HYXITZLLTYIPOF-UHFFFAOYSA-N
SMILES
O1C=C(C)C2C(=O)C(=O)C3=C(C1=2)C=CC1=C3CCCC1(C)C
LogP
4.925 (est)
CAS Datenbank
568-72-9(CAS DataBase Reference)

Sicherheit

S-S?tze: 24/25
WGK Germany  3
RTECS-Nr. SF8282695
HS Code  29321900
Speicherklasse 13 - Non Combustible Solids
Giftige Stoffe Daten 568-72-9(Hazardous Substances Data)

Tanshinone IIA Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Tanshinone IIA mainly exists in the roots of Salvia miltiorrhiza Bge. Traditional Chinese medicine Danshen, slightly cold and bitter, is often used for activating blood circulation and eliminating stasis in Chinese medicine. It can also promote blood circulation, open the energy channels, calm the heart, cool the blood, relieve swelling, remove twinge in the heart and stomach, and remove carbuncle and erysipelas. It is classified as high grade in Shen Nong’s Herbal Classic. It has been used as a traditional Chinese medicine in clinical practice for thousands of years. And it is not only recorded in the leading medical works through the ages but also in CP and USP.

Chemische Eigenschaften

Orange powder

Physikalische Eigenschaften

Appearance: brick-red crystalline powder. Melting point: 209–210°C. Solubility: absorbs moisture easily, very soluble in hot water, slightly soluble in methanol or ethanol, and practically insoluble in chloroform

History

The study of the chemical composition of Salvia miltiorrhiza began in the 1930s. Japanese scholars first extracted three kinds of liposoluble components from Danshen. They are tanshinones I, II, and III.

Verwenden

Tanshinone IIA is a derivative of Tanshinone and acts as a potential inhibitor of tumor growth in vivo. Also maintains vasodilating activity in vivo.

Pharmakologie

Long-term researches show that tanshinone exhibits a variety of pharmacological effects, such as the protection of the cardiovascular system, anti-infective effects, and antioxidant effects. As for the domestic pharmacological study of tanshinone IIA, it was first started in the Shanghai Institute of Chinese Medicine. Professor Ding Guangsheng discussed the cardiovascular effects of tanshinone IIA.He found that intraperitoneal injection of tanshinone IIA sodium sulfonate (200mg/kg) significantly prolonged the survival time of mice under hypoxia atmosphere, and an increase in cardiac output was observed in a dog under anesthesia with a one-time intravenous injection of 20 mg/kg . In recent years, the mechanism of tanshinone IIA is increasingly brought to further research. Tanshinone IIA can increase the activity of superoxide dismutase (SOD) and interfere with the pathological process of many diseases, especially in cardiovascular diseases. It can attenuate the damages from the reactive oxygen species to vascular endothelial cells, lower the risk of atherosclerosis, and reduce the formation of atheromatous plaque. tumor cells and the expression of various genes connected with the proliferation, differentiation, and apoptosis of tumor cells. It may also have something to do with the inhibition of telomerase activity in tumor cells, changes in antigen expression on tumor cell surface, etc.

Clinical Use

Tanshinone IIA is a diterpenoid quinone liposoluble ingredient of high content, and its chemical structure is the most representative in Danshen. In addition to tanshinone IIA sodium sulfonate, there are a variety of preparations of Salvia common ketone used clinically, such as tanshinone tablets, tanshinone capsules, tanshinone injection, Danshen Shuxin capsule, compound Danshen soft capsules, and compound Danshen particles.

Cytotoxicity

IC50 (μg/mL): 0.59 (A549), 0.81 (TOV-21G) and 1.9 (MIAPaCa-2), NS (MV-3)(Chang et al. 2013; Fronza et al. 2011).
IC50 (μg/mL): 2.97 (HeLa), 2.71 (KB-3-1),>2.94 (NCI-H460), 2.62 (PC3), 2.94(MCF-7), 1.62 (K562)(Wu et al. 2014)

Tanshinone IIA Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Tanshinone IIA Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 594)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907
qinhe02@xaltbio.com China 997 58
BINBO BIOLOGICAL CO.,LTD
+8618629063126
info@binbobiological.com China 477 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21587 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29815 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897
sales@biopurify.com China 4616 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768
52513593@qq.com CHINA 2972 58
Xi'an Kono chem co., Ltd.,
029-86107037 13289246953
info@konochemical.com China 1169 58
Shaanxi Pioneer Biotech Co., Ltd .
+8613259417953
sales@pioneerbiotech.com China 1287 58
NanJing Spring & Autumn Biological Engineering CO., LTD.
+8613815430202
sale02@cqherb.com CHINA 376 58

568-72-9()Verwandte Suche:


  • AKOS NCG1-0066
  • 3,8,8-TRIMETHYL-8,9,10,11-TETRAHYDROPHENANTHRO[1,2-B]FURAN-1,2-DIONE
  • TANSHINONE IIA 98+%
  • 1,6,6-TRIMETHYL-6,7,8,9-TETRAHYDRO-PHENANTHRO[1,2-B]FURAN-10,11-DIONE
  • TANSHINONE IIA
  • TANSHINONES IIA
  • tanshiones
  • Tanshionesiia
  • TANSHINONE IIA 98%
  • TANSHINONE IIA 98+% HPLC
  • TANSHION P.E 20%
  • SweetOrange
  • TANSHINONE A
  • TANSHINONE IIA(P)
  • Salvia quinone A
  • Phenanthro[1,2-b]furan-10,11-dione,6,7,8,9-
  • tetrahydro-1,6,6-trimethyl-
  • 6,7,8,9-Tetrahydro-1,6,6-trimethylphenanthro[1,2-b]furan-10,11-dione
  • Dan Shen ketone
  • Sodium Tanshinone IIA Silate
  • Tanshine II
  • Stone lotus leaf extract
  • Tanshinone II A (Salvia quinone A)
  • Tanshinone IIA (Tanshinone B)
  • Phenanthro [1, 2-b]furan-10, 11-dione, 6, 7, 8, 9-tetrahydro-1, 6, 6-triMethy
  • Tanshinone ⅡA, froM Salvia Miltiorrhiza
  • Tanshinone IIA (20 mg)
  • ANSHINONE ⅡA
  • Tanshinonel IIA
  • Tanshinone IIA, 97%, from Salvia miltiorrhiza Bunge
  • 1,6,6-trimethyl-2,7,8,9-tetrahydro-1H-naphtho[1,2-g]benzofuran-10,11-dione
  • 1,6,6-trimethyl-8,9-dihydro-7H-naphtho[1,2-g]benzofuran-10,11-dione
  • Tanshinone IIA 568-72-9
  • Tanshinone IIA, 97%, from Salvia miltiorrhiza
  • Tanshinone IIa CRS
  • 2A tanshinone
  • Tanshinone IIA (Dan Shen ketone)
  • ATanshinoneⅡA
  • Tanshinone IIA (1643339)
  • Tanshinone 2A
  • Tanshinone IIA (7CI)
  • Tanshinone IIA-RM
  • Abametapir Impurity 26
  • Salvia Miltiorrhiza Extract, Danshen Root Extract Tanshinone IIA
  • Tanshinonum ⅡA
  • TanshinoneⅡA
  • Tanshinone IIA Reference Standard
  • Tanshinone IIA (Standard)
  • Tanshinone B
  • TANSHINONE ⅡA
  • 568-72-9
  • 8568-72-9
  • C19H18O3
  • Inhibitors
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
Copyright 2019 ? ChemicalBook. All rights reserved
韶山市| 分宜县| 河北省| 莱芜市| 确山县| 三都| 衡南县| 普兰店市| 民和| 屯门区| 淳安县| 东辽县| 和静县| 大田县| 商城县| 宝鸡市| 高尔夫| 卢氏县| 望城县| 雷山县| 沅陵县| 辛集市| 景泰县| 上栗县| 南安市| 永寿县| 普格县| 桐梓县| 德州市| 丹凤县| 扶沟县| 永宁县| 海晏县| 常山县| 右玉县| 类乌齐县| 福海县| 贵溪市| 巍山| 长泰县| 太白县|