Heptafluorbuttersure
|
|
|
- CAS-Nr.
- 375-22-4
- Bezeichnung:
- Heptafluorbuttersure
- Englisch Name:
- Heptafluorobutyric acid
- Synonyma:
- HFBA;Perfluorobutanoic acid;PERFLUOROBUTYRIC ACID;2,2,3,3,4,4,4-Heptafluorobutanoic acid;PERFLUOROBUTYRATE;heptafluorobutanoicacid;TIMTEC-BB SBB008777;Perfluorobutanoicaid;HEPTAFLUOROBUTYRC ACID;FC-23
- CBNumber:
- CB5853573
- Summenformel:
- C4HF7O2
- Molgewicht:
- 214.04
- MOL-Datei:
- 375-22-4.mol
|
Heptafluorbuttersure Eigenschaften
- Schmelzpunkt:
- -17.5 °C
- Siedepunkt:
- 120 °C755 mm Hg(lit.)
- Dichte
- 1.645 g/mL at 25 °C(lit.)
- Dampfdichte
- 7 (vs air)
- Dampfdruck
- ~10 mm Hg ( 25 °C)
- Brechungsindex
- n20/D 1.3(lit.)
- Flammpunkt:
- 120-121°C
- storage temp.
- Store below +30°C.
- L?slichkeit
- Chloroform: soluble; Methanol: soluble
- pka
- pK1:0.17 (25°C)
- Aggregatzustand
- Powder
- Wichte
- approximate 1.6
- Farbe
- Clear colorless to faint yellow
- PH
- 1 (H2O, 20℃)
- Wasserl?slichkeit
- miscible
- Sensitive
- Light Sensitive
- BRN
- 1426882
- Henry's Law Constant
- 8.1×10-1 mol/(m3Pa) at 25℃, Kwan (2001)
- InChI
- 1S/C4HF7O2/c5-2(6,1(12)13)3(7,8)4(9,10)11/h(H,12,13)
- InChIKey
- YPJUNDFVDDCYIH-UHFFFAOYSA-N
- SMILES
- OC(=O)C(F)(F)C(F)(F)C(F)(F)F
- CAS Datenbank
- 375-22-4(CAS DataBase Reference)
- NIST chemische Informationen
- Butanoic acid, heptafluoro-(375-22-4)
- EPA chemische Informationen
- Heptafluorobutyric acid (375-22-4)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
C |
|
|
| R-S?tze: |
34-35 |
|
|
| S-S?tze: |
26-36/37/39-45 |
|
|
| RIDADR |
UN 3265 8/PG 2 |
|
|
| WGK Germany |
3 |
|
|
| RTECS-Nr. |
ET4025000 |
|
|
| F |
3-8-10 |
|
|
| Hazard Note |
Corrosive |
|
|
| TSCA |
TSCA listed |
|
|
| HazardClass |
8 |
|
|
| PackingGroup |
II |
|
|
| HS Code |
29159000 |
|
|
| Speicherklasse |
8A - Combustible corrosive hazardous materials |
|
|
| Hazard Classifications |
Eye Dam. 1
Skin Corr. 1A |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Achtung
|
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H290 |
Kann gegenüber Metallen korrosiv sein. |
Korrosiv gegenüber Metallen |
Kategorie 1 |
Warnung |
|
P234, P390, P404 |
| H314 |
Verursacht schwere Ver?tzungen der Haut und schwere Augensch?den. |
?tzwirkung auf die Haut |
Kategorie 1B |
Achtung |
|
P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501 |
|
| Sicherheit |
| P234 |
Nur im Originalbeh?lter aufbewahren. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P301+P330+P331 |
BEI VERSCHLUCKEN: Mund ausspülen. KEIN Erbrechen herbeiführen. |
| P303+P361+P353 |
BEI BERüHRUNG MIT DER HAUT (oder dem Haar): Alle kontaminierten Kleidungsstücke sofort ausziehen. Haut mit Wasser abwaschen oder duschen. |
| P363 |
Kontaminierte Kleidung vor erneutem Tragen waschen. |
| P390 |
Verschüttete Mengen aufnehmen, um Materialsch?den zu vermeiden. |
| P406 |
In korrosionsbest?ndigem/… Beh?lter mit korrosionsbest?ndiger Auskleidung aufbewahren. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
|
Heptafluorbuttersure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R34:Verursacht Ver?tzungen.
R35:Verursacht schwere Ver?tzungen.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
Chemische Eigenschaften
Clear colorless to faintly yellow liquid
Verwenden
Heptafluorobutyric acid (HBFA) has been used widely for purifying neuropeptides because of its excellent resolution. The use of heptafluorobutyric acid as a volatile ion-pair reagent in the high-performance liquid chromatographic isolation of SB-223070 John K.
Heptafluorobutyric acid is a strong acid and ion-pairing agent that is used in analytical chemistry, notably in HPLC and in gas chromatography/mass spectrometry (GC/MS), in a similar manner to trifluoroacetic acid (TFA). The strong acidity of HFBA ensures that other acidic groups such as carboxylic acid moieties on biomolecules remain protonated, and thus the biomolecule samples are able to interact with organic solvents in such processes as reverse phase chromatography. The longer alkyl chain of HFBA makes it more hydrophobic than TFA, and thus HFBA can be utilized with more hydrophobic samples.
HFBA (0.1%) has been used in the mobile phase of an HPLC/LC-MS protocol for the detection of marine bacterioplankton sideophores.A study of the effects of various acids, including HFBA, on the resolution of intact proteins by reversed-phase LC/ESI-MS has been published.A modified version of the peptide ladder sequencing technique that incorporates allyl isothiocyanate and HFBA has been reported.
Definition
ChEBI: A monocarboxylic acid that is perfluorinated butyric acid.
Allgemeine Beschreibung
Perfluorobutyric acid is an effective additive for zinc electrodeposition.
Hazard
Irritant to tissue.
l?uterung methode
Fractionally distil the acid twice in an Oldershaw column (p 10) with an automatic vapour-dividing head, the first distillation being in the presence of conc H2SO4 as a drying agent. (Take care with the hot acid.) [Beilstein 2 IV 810.]
Heptafluorbuttersure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Pentafluorpropionsure
Cyclopropanecarboxylic acid, 2,2,3,3-tetrafluoro-1-(trifluoromethyl)-
Perfluorvaleriansure
Undecafluorhexansure
Pentadecafluoroctansure
Pivaloylchlorid
Trifluoressigs?ure
Perfluorheptansure
2,2,4,4-Tetramethylpentan-3-on
Butanamide, 2,2,3,3,4,4,4-heptafluoro-N-(2,2,3,3,4,4,4-heptafluoro-1-oxobutyl)-
1H-HEPTAFLUOROPROPANE
Downstream Produkte
Heptafluorbuttersure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 313)Lieferanten
375-22-4(Heptafluorbuttersure)Verwandte Suche:
- N-HEPTAFLUOROBUTYRIC ACID
- PERFLUOROBUTBUTYRIC ACID
- RARECHEM AL BO 0423
- HEPTAFLUOROBUTYRIC ACID, FOR ION CHROMATOGRAPHY
- HEPTAFLUOROBUTYRIC ACID FOR PROTEIN SEQ.
- Heptafluorobutyric acid Solution
- HEPTAFLUOROBUTYRIC ACID, FOR PROTEIN SEQ UENTIAL ANALYSIS
- Heptafluorobutyric Acid (ca. 0.5mol/L in Water) [Ion-Pair Reagent for LC-MS]
- EDMAN REAGENT NO 3
- HEPTAFLURORBUTYRIC ACID
- HEPTAFLUOROBUTYRIC ACID
- HEPTAFLUORO-N-BUTYRIC ACID
- IPC-PFFA-4
- FC-23
- HAPTAFLUORO-N-BUTYRIC ACID
- Heptafluorobutyric acid, for protein sequence analysis, 99%
- Heptafluorobutyricacid99%
- HEPTAFLUOROBUTYRIC ACID, 99%, FOR PROTEIN SEQUENCE ANALYSIS
- 1-[N-(2,6-Xylyl)glycyl]pyrrolidine
- Heptafluorobutyric Acid [Sequenation Reagent]
- Edman Reagent No. 3, Heptafluorobutyric acid, HFBA, Perfluorobutyric acid
- Edman Reagent No. 3, HFBA, Perfluorobutyric acid
- Heptafluorobutyric acid solution,HFBA solution, Perfluorobutbutyric acid solution
- Heptafluorobutyric acid,Edman Reagent No. 3, HFBA, Perfluorobutyric acid
- Heptafluorobutyric acid, 99,5 %
- Perfluorobutyric acid,Edman Reagent No. 3, HFBA, Heptafluorobutyric acid, Perfluorobutyric acid
- heptafluoro-Butanoicacid
- Heptafluorobutyric acid acid
- heptafluoro-butyricaci
- Kyselina heptafluormaselna
- kyselinaheptafluormaselna
- Perfluorbuttersαure
- Perfluorobutanoicacid
- Perfluoropropanecarboxylic acid
- Heptafluorobutyric acid, Perfluorobutanoic acid
- [Sequenation Reagent]
- Heptafluorobutyric Acid
- Heptafluorobutyric acid, 99% 100GR
- Heptafluorobutyric acid, 99% 25GR
- Fluorad FC 23
- H 0024
- NSC 820
- IPC-PFFA-4
Perfluorobutyric Acid
- HFBA
Perfluorobutyric Acid
- (ca. 0.5Mol/L in Water) [Ion-Pair Reagent for LC-MS]
- IPC-PFFA-4 (ca. 0.5mol/L in Water)
- 2,2,3,3,4,4,4-heptafluoro-butyricacid
- butanoicacid,heptafluoro-
- Butyric acid, heptafluoro-
- butyricacid,heptafluoro-
- Heptafluorbuttersαure
- Heptafluoro-1-butanoic acid
- Heptafluoro-1-butanoicacid
- Heptafluorobutanoic acid
- heptafluoro-butanoicaci
- Butanoic acid,2,2,3,3,4,4,4-heptafluoro-
- Perfluorobutyric acid 98%
- HFBA/ Heptafluorobutyric acid
