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Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate

Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Struktur
85267-60-3
CAS-Nr.
85267-60-3
Englisch Name:
Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate
Synonyma:
3',5'-di-O-acetyl-2'-deoxy-5-((trimethylsilyl)ethynyl)uridine;Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate
CBNumber:
CB59007160
Summenformel:
C18H24N2O7Si
Molgewicht:
408.48
MOL-Datei:
85267-60-3.mol

Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Eigenschaften

Dichte
1.27±0.1 g/cm3(Predicted)
pka
8.83±0.10(Predicted)
InChI
InChI=1S/C18H24N2O7Si/c1-11(21)25-10-15-14(26-12(2)22)8-16(27-15)20-9-13(6-7-28(3,4)5)17(23)19-18(20)24/h9,14-16H,8,10H2,1-5H3,(H,19,23,24)/t14-,15+,16+/m0/s1
InChIKey
QPBVAPCEENIYRQ-ARFHVFGLSA-N
SMILES
C(OC(=O)C)[C@H]1O[C@@H](N2C=C(C#C[Si](C)(C)C)C(=O)NC2=O)C[C@@H]1OC(=O)C

Sicherheit

Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

3',5'-di-O-acetyl-2'-deoxy-5-((trimethylsilyl)ethynyl)uridine can be used as organic intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthese

1.jpg
1.Add DMAP (0.16 mmol, 20 mg) to a stirred suspension of 2'-deoxyuridine (1 mmol, 228 mg) in acetic anhydride (7.5 mL).2.Observe the reaction mixture become homogenous for 6 hours.3.Remove the volatiles in vacuum.4.Purify the residue by flash chromatography on silica gel eluted with EA/cyclohexane (4:1 → 19:1, v/v) to obtain 3',5'-di-O-acetyl-2'-deoxyuridine.

Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 2)Lieferanten
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NewCan Biotech Limited +86-0571-86912261 +86-15658003402
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Zhengzhou Nucleosides Biotech Co., Ltd. 15981919713 15981919713
sales@nucleosides.com China 471 58

  • Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate
  • 3',5'-di-O-acetyl-2'-deoxy-5-((trimethylsilyl)ethynyl)uridine
  • 85267-60-3
  • C18H24N2O7Si
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