2-Hydroxyethansulfonsure, Verbindung mit 4,4'-[Hexan-1,6-diylbis(oxy)]bis[benzolcarboxamidin] (2:1) Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

White or slightly yellow powder, hygroscopic

Verwenden

hexamidine diisethionate is an anti-microbial and preservative targeting fungi and yeast. It may also have some emollient capacities.

Application

Hexamidine Diisethionate is a preservative, antibacterial, and anti-inflammatory agent extensively used in cosmetics and personal care products. It prevents bacterial and fungal growth in formulations as well as fights off acne-causing bacteria on the skin. This synthetic ingredient is often used alongside other preservatives to enhance its effectiveness in improving the shelf life of beauty formulations. Hexamidine Diisethionate is ideal for sensitive skin to reduce redness or irritation, especially in eczema-prone or rosacea-prone skin.

Kontakt-Allergie

Hexamidine is an antiseptic active against Grampositive bacteria and fungi, used as a disinfectant and a preservative in cosmetics. It induces papulo-vesicular and diffuse allergic contact dermatitis.

Toxikologie

Acute oral LD(50) values of Hexamidine Diisethionate were 0.71 to 2.5 g/kg in mice and 0.75 g/kg in rats. Dermal exposure to 4 g/kg Hexamidine Diisethionate in rats or up to 9.4 ml/kg of a 0.1% Hexamidine Diisethionate solution under occlusion in rabbits produced no mortality or other signs of toxicity. The no-observed-effect level (NOEL) for oral subchronic toxicity of Hexamidine Diisethionate in rats was 50 mg/kg/day. No signs of toxicity were observed with 2% Hexamidine Diisethionate in subchronic studies using rabbits. Application of 0.1 ml of 0.11% Hexamidine Diisethionate in aqueous solution to the eyes of rabbits produced transient reactions; 0.05% produced no reactions. Slight erythema was observed with 0.10% Hexamidine Diisethionate applied to the abraded skin of 1/11 albino rabbits. A 40% solution of Hexamidine Diisethionate applied to 10% of the body surface of rats produced slight erythema, slight edema, and scabbing in some animals at varying times after treatment. Hexamidine Diisethionate was not a sensitizer in the guinea pig maximization test or in an intracutaneous guinea pig sensitization test. Hexamidine Diisethionate was not a photosensitizer in albino rabbits. Hexamidine Diisethionate was not mutagenic in a bacterial reverse mutagenicity assay or clastogenic in mammalian cells. Hexamidine Diisethionate at 0.10% did not provoke primary irritation, inflammation, or sensitization in a clinical test of 200 human subjects^[1].

2-Hydroxyethansulfonsure, Verbindung mit 4,4'-[Hexan-1,6-diylbis(oxy)]bis[benzolcarboxamidin] (2:1) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

2-Hydroxyethansulfonsure, Verbindung mit 4,4'-[Hexan-1,6-diylbis(oxy)]bis[benzolcarboxamidin] (2:1) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shangdong Yuanlitai Nutratech Co.,ltd	+8618782242822	tatiana@yltnutra.com	China	8	58
QINGDAO HONG JIN CHEMCIAL CO.,LTD.	+86-86-532-83657313 +86-18663969289	hjt@hong-jin.com	China	225	58
Beri Pharma Co., Ltd.	+8613417710166	sales@zhberi.com	China	227	58
PuriPharm Co., ltd.	+86-0572-2745768 +8613816075732	sales@puripharm.com	China	1005	58
Henan Boweixin Biotechnology Co., Ltd.	+86-15617696836 +86-15617697370	bwx@bwxbiotech.com	China	18	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5228	58
ZhenYiBio Technology Inc	+8615309206328	alexxue@zhenyibio.com	China	297	58
Hebei Fengjia New Material Co., Ltd	+86-0311-87836622 +86-18712993135	sales01@tairunfaz.com	China	8051	58
Shaanxi Haibo Biotechnology Co., Ltd	+undefined18602966907	qinhe02@xaltbio.com	China	997	58

659-40-5(2-Hydroxyethansulfonsure, Verbindung mit 4,4'-[Hexan-1,6-diylbis(oxy)]bis[benzolcarboxamidin] (2:1))Verwandte Suche:

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• 2-Hydroxyethanesulphonic acid,compoundwith4,4'-[hexane-1,6-diylbis(oxy)]bis[benzenecarboxamidine](2:1)
• Ethanesulfonic acid, 2-hydroxy-, compd. with 4,4-1,6-hexanediylbis(oxy)bisbenzenecarboximidamide (2:1)
• 2-Hydroxyethansulfonsure, Verbindung mit 4,4′-(Hexan-1,6-diylbis(oxy))bis(benzolcarboxamidin) (2:1)
• 2535RP
• Esomedina
• Ophtamedine
• RP-2535
• 4-[6-(4-Carbamimidoylphenoxy)hexoxy]benzenecarboximidamide 2-hydroxyethanesulfonnate (1:2)
• HEXAMIDINE DIISETHIONATE(HD)
• EXAMIDINE DIISETHIONATE
• Hexamidine bis (isethionate) salt
• HEXAMIDINE DIISETHIONATE
• 4,4'-(Hexane-1,6-diylbis(oxy))dibenzimidamide bis(2-hydroxyethanesulfonate)
• 2-Hydroxyethanesulfonic acid - 4,4'-[1,6-hexanediylbis(oxy)]dibenzenecarboximidamide (1:1)
• 2-hydroxyethanesulphonic acid, compound with 4,4'-[hexane-1,6-diylbis(oxy)]bis[benzenecarboxamidine] (2:1)
• hexamidine disethionate
• 4,4'-Diamidino-α,ω-diphenoxyhexane isethionate
• Hexamidine diisethionate, HD100,HP100
• Hexamidine diisethionate Hexamidine diisethionate
• HP-100
• 4'-[hexane-1
• 6-diylbis(oxy)]bis[benzenecarboxamidine] (2:1)
• compound with 4
• Bioactive HD 100
• 2-hydroxyethanesulphonic acid, compound with 4,4'-[hexane-1,6-diylbis(oxy)]bis[benzenecarboxamidine] (2
• Hexamidine diisetionate CRS
• RF 2535 {Isethionate}
• High Quality Hexamidine Diisethionate Powder CAS 659-40-5
• 4,4'-(hexane-1,6-diylbis(oxy))dibenzimidamide 2-hydroxyethanesulfonate
• Hexamidine 2-hydroxyethansulfonate
• Desomedine
• Elestab HP 100
• SymCalmin
• hexamidineisetionate
• Hexamidine bis (hydroxyethyl sulfonic acid) salt
• Hexamidine dihydroxyethyl sulfonate (acid value<1)
• Hexamidine diisethionate HD-100
• Hexamidine Di(2-hydroxyethanesulfonate)
• Hexamidine di(hydroxyethyl sulfonate)salt
• Hexamethylenediamine di(hydroxyethylsulfonate)
• HD-100
• Hexamidine isethionate
• 659-40-5
• 556-67-5
• C20H26N4O22C2H6O4S
• API