AG 957 Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

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Beschreibung

Tyrphostins are tyrosine phosphorylation inhibitors that act by inhibiting tyrosine kinases. AG957 is a tyrphostin that targets transforming Bcr-Abl fusion proteins (p185^Bcr-Abl, p210^Bcr-Abl), as well as normal c-Abl (IC₅₀s = 4.3, 1, and 7.1 μM, respectively, for human proteins). It also inhibits epidermal growth factor receptor (IC₅₀ = 0.25 μM). As the constitutively-active 210 kDa Bcr-Abl fusion protein commonly occurs in chronic myelogenous leukemia (CML) cells, AG957 is commonly used to study Bcr-Abl signaling in the CML K562 cell line. AG957 is also used to study signaling through c-Abl.

Verwenden

Tyrphostin AG 957 is a potent tyrosine kinase inhibitor. Also, it causes metabolic alterations in K562 cells. It is a COVID19-related research product.

AG 957 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

AG 957 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
Nanjing Moldeep Biochemical Co., Ltd.	+86-25-58282389 +8618913958656	inquiries@moldeep.com	China	19999	58
Spectrum Chemical Manufacturing Corp.	021-021-021-67601398-809-809-809 15221380277	marketing_china@spectrumchemical.com	China	9658	60
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	025-66113011 13913916777	cfzhang@aikonchem.com	China	19906	55
AdooQ BioScience, LLC	+1 (866) 930-6790	info@adooq.com	United States	2782	58
BOC Sciences	16314854226	info@bocsci.com	United States	9923	65
Shanghai CR Corporation Limited	13062833949; 4006653949 4006653949	fred.wen@crcorporation.cn	China	9749	58

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• Lavendustin C Analog, Methyl-4-[N-(2μ,5μ-dihydroxybenzyl)amino]benzoate
• NSC 654705
• TYRPHOSTIN 957
• TYRPHOSTIN AG 957
• AG 957
• 4-AMINO-N-(2,5-DIHYDROXYBENZYL)METHYL BENZOATE
• LAVENDUSTIN C ANALOG
• METHYL-4-[N-(2',5'-DIHYDROXYBENZYL)AMINO]BENZOATE
• Benzoic acid, 4-[[(2,5-dihydroxyphenyl)methyl]amino]-, methyl ester
• paxillin,NSC654705,c-Abl,Bcr-Abl,lipopolysaccharide,Tyrphostin AG-957,integrins,leukemia,tyrosine,Tyrphostin AG 957,hematopoiesis,AG-957,NSC-654705,AG 957,NSC 654705,AG957,Tyrphostin AG957,kinase,BCR/ABL,inhibit,cytoskeleton,Inhibitor,Chronic,myelogenous
• Tyrphostin AG 957, p210 tyrosine kinase inhibitor
• AG957, 10 mM in DMSO
• Methyl 4-((2,5-dihydroxybenzyl)amino)benzoate
• 140674-76-6
• Tyrosine Kinase (TK)
• Receptor Tyrosine Kinase Inhibitors
• Kinase/Phosphatase Biology
• Cell Biology
• Cell Signaling and Neuroscience
• BioChemical