Fas Ligand, Human, Recombinant Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

Recombinant, human, Fas ligand consisting of amino acids 103-281 fused at the N-terminus to a tag-linker peptide. Binds to human, mouse, and rat Fas. The recombinant protein is produced in HEK293 cells. Useful for cytotoxicity assays.



Fas/APO1/CD95 (37-42 kDa), a member of the Tumor Necrosis Factor/Nerve Growth Factor (TNF/NGF) receptor family, is an apoptosis-signaling surface receptor known to trigger apoptotic cell death. Homology exists between the Fas and TNF receptors including a region called the "death domain" which is required to propagate the apoptotic signal. The signal activates a family of cysteine proteases, or caspases, which systematically lead to cell destruction. Genetic defects in the Fas system have been shown to lead to autoimmune disorders while increased activity or deregulation contributes to the pathology of diseases such as AIDS.

Fas Ligand, Human, Recombinant Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Fas Ligand, Human, Recombinant Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51395	80
Merck Millipore	--	bioscience@merckgroup.com	China	6839	58
Merck KGaA	--	ordercn@merckgroup.com	China	6394	58

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• Fas Ligand, Human, Recombinant