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Triptorelin acetate

Triptorelin acetate Struktur
140194-24-7
CAS-Nr.
140194-24-7
Englisch Name:
Triptorelin acetate
Synonyma:
TRIPTORELIN ACETATE;OvuGel;LHRH-A3;AY 25650;Wy 42422;Wy 42462;BIM 21003;BIM 21003C;Decapeptyl-Depot;Triptelin Acetate
CBNumber:
CB61106806
Summenformel:
C64H82N18O13.C2H4O2
Molgewicht:
1371.52
MOL-Datei:
140194-24-7.mol

Triptorelin acetate Eigenschaften

L?slichkeit
Aqueous Base (Slightly), Methanol (Very Slightly, Heated, Sonicated), Water (Slightly)
Aggregatzustand
Solid
Farbe
White to Off-White
Stabilit?t:
Hygroscopic
InChIKey
HPPONSCISKROOD-UXTGTKPXNA-N
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) Health Hazard (GHS08)
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H360 Kann die Fruchtbarkeit beeintr?chtigen oder das Kind im Mutterleib sch?digen. Fertility (Fruchtbarkeit) Kategorie 1 Achtung
Sicherheit

Triptorelin acetate Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Triptorelin acetate (TA) is a GnRH agonist that was earlier used as a veterinary drug for a single fixed-time artificial insemination through the synchronised estrous cycle of weaned sows. The risk assessment was that the Food Safety Commission of Japan (FSCJ) concluded that TA is not likely to cause adverse effects on human health through dietary exposure. Because TA does not have genotoxicity relevant to human health and is degraded in the digestive tract, its oral bioavailability is low. TA is currently used for the treatment of central precocious puberty and assisted reproduction. Injectable TA alone or in combination with levonorgestrel intrauterine device is also used to treat endometrial atypical hyperplasia (EAH) . Combination therapy is more effective, improving patients' menstrual abnormalities, endometrial thickening and quality of life, and is safe.

Chemische Eigenschaften

White Solid

Verwenden

Synthetic peptide agonist analog of LH-RH. Triptorelin acetate is a potent agonist of LH-releasing hormone, currently used in the treatment of prostatic cancer where therapy may be required over months or years. Antineoplastic (hormonal). Used in the treatment of endometriosis and infertility.

Nebenwirkungen

Triptorelin acetate has been reported to have a possible side effect of severe bone loss. The first report was of an 8-year-old girl with central precocious puberty who experienced anaphylactic shock after the first injection of decapeptide containing triptorelin acetate (D,L lactide coglycolide), dextran 70, and polysorbate 80. However, it is also possible that it was a reaction to the polysorbate. Therefore, doctors should be aware of immediate reactions to drugs containing polysorbates.

Triptorelin acetate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Triptorelin acetate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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140194-24-7()Verwandte Suche:


  • 6-D-Tryptophan Luteinizing HorMone-Releasing Factor (Pig) Acetate
  • 6-D-Tryptophan Luteinizing HorMone-Releasing Factor (Swine) Acetate
  • BIM 21003C
  • Decapeptyl-Depot
  • OvuGel
  • Triptorelin Acetate OR Triptorelin PaMoate
  • Triptelin Acetate
  • Triptorelin Acetate CAS 140194-24-7 (acetate)
  • Triptorelin?Acetate impurity
  • Triptorelin AcetateQ: What is Triptorelin Acetate Q: What is the CAS Number of Triptorelin Acetate Q: What is the storage condition of Triptorelin Acetate Q: What are the applications of Triptorelin Acetate
  • Triptorelin Acetate(acetate)
  • AY 25650
  • BIM 21003
  • Wy 42422
  • Wy 42462
  • TRIPTORELIN ACETATE
  • Luteinizing hormone-releasing factor (swine), 6-D-tryptophan-, acetate (1:1)
  • 6-D-tryptophan-Luteinizing hormone-releasing factor (swine) acetate (1:1)
  • Triptorelin acetate(57773634 free base),Triptorelin acetate(57773 63 4 free base)
  • Triprerelin acetate
  • LHRH-A3
  • Triptorelin acetate 100 μg/mL in Acetonitrile:Methanol
  • 140194-24-7
  • 73049-97-9
  • C64H82N18O13C2H4O2
  • C66H86N18O15
  • Pharmaceuticals
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Peptides
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