PSEUDOLARIC ACID B
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- CAS-Nr.
- 82508-31-4
- Englisch Name:
- PSEUDOLARIC ACID B
- Synonyma:
- PLAB;Pseudolaric acid;Pseudolarix acid B;PSEUDOLARIC ACID B;Pseudolaric acid B-RM;(-)-Pseudolaric Acid B;Pseudolaric Acid B(PBA);7-Di-O-methylnaringenin;Pseudolaric Acid B
(PAB);Pseudolaric Acid B (Standard)
- CBNumber:
- CB6117700
- Summenformel:
- C23H28O8
- Molgewicht:
- 432.46
- MOL-Datei:
- 82508-31-4.mol
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PSEUDOLARIC ACID B Eigenschaften
- Schmelzpunkt:
- 166°C
- Siedepunkt:
- 466.14°C (rough estimate)
- Dichte
- 1.2108 (rough estimate)
- Brechungsindex
- 1.4480 (estimate)
- storage temp.
- 2-8°C
- L?slichkeit
- methanol: soluble1mg/mL, clear, colorless
- Aggregatzustand
- powder or crystals
- pka
- 4.52±0.19(Predicted)
- Farbe
- white to off-white
- InChIKey
- VDGOFNMYZYBUDT-YCONPBHISA-N
- SMILES
- C1(=O)O[C@@](/C=C/C=C(/C(O)=O)\C)(C)[C@]2([H])CC[C@@]31CC=C(C(OC)=O)CC[C@@]32OC(C)=O
PSEUDOLARIC ACID B Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Pseudolaric acid B (PAB) is a diterpene acid isolated from the bark of
P. kaempferi, a traditional Chinese medicinal plant. It has reported antifungal activities, consistent with its traditional use in the treatment of dermatological fungal infections. Moreover, PAB has diverse effects that are relevant to cancer therapy, including inducing apoptosis of cancer cells (IC
50 = ~1 μM), preventing angiogenesis, and inhibiting tumor growth
in vivo.
Verwenden
(-)-Pseudolaric Acid B is a diterpenoid posessing an immunomodulatory effect. It acts as an immunosuppressant in vitro/vivo however does show some cytotoxicity. Anti-tumor agent as well.
PSEUDOLARIC ACID B Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
PSEUDOLARIC ACID B Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 254)Lieferanten
82508-31-4()Verwandte Suche:
- Pseudolaric acid
- Pseudolaric Acid B
(PAB)
- Pseudolaric Acid B(PBA)
- -1,3-pentadienyl)3,4,4a,5,6,9-hexahydro-3-methyl-1-oxo-,7-methylester,(3-al
- 1h-4,9a-ethanocyclohepta(c)pyran-7-carboxylicacid,4a-(acetyloxy)-3-(4-carboxy
- pha(1e,3e),4-alpha,4a-alpha,9a-alpha)-(-)-(9ci)
- PSEUDOLARIC ACID B
- PLAB
- 1H-4,9a-Ethanocyclohepta[c]pyran-7-carboxylicacid,4a-(acetyloxy)-3-[(1E,3E)-4-carboxy-1,3-pentadien-1-yl]-3,4,4a,5,6,9-hexahydro-3-methyl-1-oxo-,7-methyl ester, (3R,4S,4aS,9aR)-
- Pseudolarix acid B
- Pseudolaric acid B, 98%, from Pseudolarix amabilis (J. Nelson) Rehder
- (-)-Pseudolaric Acid B
- (2E,4E)-5-((3R,4S,4aS,9aS)-4a-acetoxy-7-(methoxycarbonyl)-3-methyl-1-oxo-3,4,4a,5,6,9-hexahydro-1H-4,9a-ethanocyclohepta[c]pyran-3-yl)-2-methylpenta-2,4-dienoic acid
- 7-Di-O-methylnaringenin
- (2E,4E)-5-((3R,4S,4aS,9aR)-4a-Acetoxy-7-(methoxycarbonyl)-3-methyl-1-oxo-3,4,4a,5,6,9-hexahydro-1H-4,9a-ethanocyclohepta[c]pyran-3-yl)-2-methylpenta-2,4-dienoic acid
- Pseudolaric acid B-RM
- Pseudolaric Acid B, 10 mM in DMSO
- Pseudolaric Acid B (Standard)
- 82508-31-4
- C23H28O8
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Inhibitors
