Orgoteine Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Orgotein is the
name applied to a group of metalloproteins obtained from various tissuesources,
such as hemolyzed plasma-free bovine erythrocytes or beef liver. They are
copper – zinc/protein chelates with molecular
masses of about 34 000. These compounds have
potent superoxide dismutase activity. When administered directly into the joint at 4 mg/week
for 6weeks, marked improvement in the mobility of acute rheumatoid patients occurred.
Synovial fluid levels of rheumatoid factor and
prostaglandin E2 were reduced.
Verwenden
Anti-inflammatory;antirheumatic.
Weltgesundheitsorganisation (WHO)
Orgotein, bovine superoxide dismutase with anti-inflammatory
activity, was introduced in 1968 for the management of rheumatic disorders and for the amelioration of side-effects of radiotherapy. Although not widely registered, it
remains available in other countries.
Sicherheitsprofil
Poison by intravenous and intraperitoneal routes. An experimental teratogen.
Orgoteine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
