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Amicetin-A

Amicetin-A Struktur
17650-86-1
CAS-Nr.
17650-86-1
Englisch Name:
Amicetin-A
Synonyma:
amicetin;Amicetin-A;Amomycin A;Benzamide, 4-[[(2S)-2-amino-3-hydroxy-2-methyl-1-oxopropyl]amino]-N-[1-[(2R,5S,6R)-5-[[4,6-dideoxy-4-(dimethylamino)-α-D-glucopyranosyl]oxy]tetrahydro-6-methyl-2H-pyran-2-yl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-
CBNumber:
CB61244964
Summenformel:
C29H42N6O9
Molgewicht:
618.68
MOL-Datei:
17650-86-1.mol

Amicetin-A Eigenschaften

Schmelzpunkt:
244-245°
alpha 
D24 +116.5° (c = 0.5 in 0.1N HCl)
Siedepunkt:
660.6°C (rough estimate)
Dichte
1.2721 (rough estimate)
Brechungsindex
1.6400 (estimate)
pka
pKa = 10.4, 7.0(at 25℃)

Sicherheit

Toxizit?t LD50 of citrate complex, pH 6 (mg/kg) in mice: ~90 i.v., 600-700 s.c.; in rats: ~200 i.v., ~600 s.c. (DeBoer)

Amicetin-A Chemische Eigenschaften,Einsatz,Produktion Methoden

Enzyminhibitor

These pyrimidine-containing glycoside antibiotic (FWAmicetin-A = 617.69 g/mol (free base); CAS 17650-86-1; FWAmicetin-B = 532.59 g/mol (free base)) from Streptomyces vinaceus-drappus and S. fasciculatus inhibits protein biosynthesis, exerting its bacteriostatic most potently on Grampositive bacteria. Amicetin B, also called plicacetin, was isolated from Streptomyces plicatus and has the identical structure minus the amethylseryl residue. It is weaker in action compared to amicetin A. Target(s): peptidyltransferase; peptidyl-tRNA hydrolase, or aminoacyl-tRNA hydrolase; ribonuclease P; protein biosynthesis.

Amicetin-A Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Amicetin-A Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 5)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
BOC Sciences
16314854226; +16314854226
inquiry@bocsci.com United States 19853 58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
+8618791163155
18791163155@163.com China 3397 58
Zhejiang Huida Biotech Co., LTD 0571-89903022 18679456698
zilong@hizyme.com China 8000 58
Biosynth Biological Technology (Suzhou) Co Ltd --
sales@biosynth.com China 6051 58

17650-86-1()Verwandte Suche:


  • Amicetin-A
  • Benzamide, 4-[[(2S)-2-amino-3-hydroxy-2-methyl-1-oxopropyl]amino]-N-[1-[(2R,5S,6R)-5-[[4,6-dideoxy-4-(dimethylamino)-α-D-glucopyranosyl]oxy]tetrahydro-6-methyl-2H-pyran-2-yl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-
  • Amomycin A
  • amicetin
  • 17650-86-1
  • C29H42N6O9
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