Benzgalantamine gluconate Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Benzgalantamine is a prodrug of galantamine. Gastrointestinal adverse effects are the most frequently reported side effects in patients undergoing treatment with cholinesterase inhibitors, including galantamine, and are often a reason for treatment discontinuation. As a prodrug, benzagalantamine remains inert as it passes through the stomach, thereby avoiding many of the gastrointestinal effects associated with peripheral cholinesterase inhibition.
Benzgalantamine was approved by the FDA in July 2024 for the treatment of mild-to-moderate dementia in Alzheimer's patients.
Chemische Eigenschaften
Benzgalantamine gluconate is derived from the dried flowers of Lycoris radiata (family Amaryllidaceae, formerly classified as Liliaceae/Lycoraceae). It occurs as a white or off-white crystalline powder, odorless with a bitter taste. It is soluble in water, slightly soluble in ethanol, almost insoluble in acetone, trichloromethane and ether.
Benzgalantamine gluconate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
