thielavin A Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Thielavin A is a fungal metabolite originally isolated from T. terricola that is related to thielavin B . Thielavin A inhibits COX, blocking both the conversion of arachidonic acid to prostaglandin H₂ (PGH₂; ) and the conversion of PGH₂ to PGE₂ (; IC₅₀s = 10 and 40 μM, respectively). Thielavin A also inhibits glucose-6-phosphatase in rat liver microsomes (IC₅₀ = 4.6 μM). It is a non-competitive inhibitor of α-glucosidase from S. cerevisiae (IC₅₀ = 23.8 μM; K_i = 27.8 μM).

Verwenden

The fungal metabolite, thielavin A, and its relatives are glucose-6-phosphatase inhibitors. The three benzoic acid units are essential for inhibition. Thielavin A was originally isolated as a inhibitor of prostaglandin biosynthesis. The closely related thielavin B is a telomerase and cell wall transglycosylation inhibitor.

thielavin A Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

thielavin A Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9804	58
Lynnchem	86-(0)29-85992781 17792393971	info@lynnchem.com	China	4587	58
Novachemistry	44-20819178-90 02081917890	info@novachemistry.com	United Kingdom	4381	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 +86-13028896684;	sales@rrkchem.com	China	57422	58
Meng Cheng Technology (Shanghai) Co., LTD	400-820-6829	sales@mitachieve.com	China	8860	58
TargetMol Chemicals Inc.	4008200310 15002144251	marketing@tsbiochem.com	China	24959	58
Shanghai Saikerui Biotechnology Co. , Ltd.	021-58000709 13162935620	sales@scrbio.com	China	9886	58

71950-66-8()Verwandte Suche:

---

• thielavin A
• 4-[(2,4-Dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethylbenzoic acid 4-carboxy-3-hydroxy-2,5,6-trimethylphenyl ester
• Benzoic acid, 4-[(2,4-dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethyl-, 4-carboxy-3-hydroxy-2,5,6-trimethylphenyl ester
• 71950-66-8