ANTI-AQUAPORIN 2
|
|
|
- CAS-Nr.
- Englisch Name:
- ANTI-AQUAPORIN 2
- Synonyma:
- ANTI-MCH-CD;ANTI-AQP-CD;ANTI-AQUAPORIN 2;ANTI-WATER CHANNEL AQUAPORIN 2;Anti-Water Channel Aquaporin 2 antibody produced in rabbit
- CBNumber:
- CB6142986
- Summenformel:
- Molgewicht:
- 381.28
- MOL-Datei:
- Mol file
|
ANTI-AQUAPORIN 2 Eigenschaften
- storage temp.
- −20°C
- Aggregatzustand
- lyophilized powder
- Biologische Quelle
- rabbit
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
T |
|
|
| R-S?tze: |
25-32-52/53 |
|
|
| S-S?tze: |
45-61 |
|
|
| WGK Germany |
3 |
|
|
| Speicherklasse |
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects |
|
|
| Hazard Classifications |
Acute Tox. 3 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Aquatic Chronic 3 |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Achtung
|
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H311 |
Giftig bei Hautkontakt. |
Akute Toxizit?t dermal |
Kategorie 3 |
Achtung |
|
P280, P302+P352, P312, P322, P361,P363, P405, P501 |
| H412 |
Sch?dlich für Wasserorganismen, mit langfristiger Wirkung. |
Langfristig (chronisch) gew?ssergef?hrdend |
Kategorie 3 |
|
|
P273, P501 |
|
| Sicherheit |
| P273 |
Freisetzung in die Umwelt vermeiden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
|
ANTI-AQUAPORIN 2 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-Water Channel Aquaporin 2 antibody is also suitable for use in chemiluminescent western blot (1:200-1:1000), and immunoblot.
Allgemeine Beschreibung
Aquaporin 2 (AQP2) is a water channel protein that regulates water balance in renal connecting tubules and collecting ducts. AQP2 is activated by anti-diuretic hormone and subsequently facilitates water inflow in renal cells. This protein also interacts with integrin to modulate epithelial cell morphogenesis and cell movement . Anti-Water Channel Aquaporin 2 antibody recognizes aquaporin 2 from rat by immunoblotting. The antibody also reacts with mouse and human AQP2.
Biochem/physiol Actions
Aquaporin (AQP2) N-terminal region plays a key role in trafficking. The C-terminal phosphorylation is crucial for the water permeability function of the apical membrane. Also, ubiquitination at lysine 270 is needed for AQP2 sorting and degradation in lysosomes or elimination through exosomes. Mutation in AQP2 gene is implicated in congenital nephrogenic diabetes insipidus (NDI), a water balance disorder. The functional dysregulation of AQP2 is also correlated to preeclampsia, congestive heart failure and liver cirrhosis.
ANTI-AQUAPORIN 2 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
ANTI-AQUAPORIN 2 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 9)Lieferanten
- Anti-Water Channel Aquaporin 2 antibody produced in rabbit
- ANTI-AQUAPORIN 2
- ANTI-AQP-CD
- ANTI-MCH-CD
- ANTI-WATER CHANNEL AQUAPORIN 2
- BioChemical
- Antibodies to Voltage-Gated Ion Channels
- Antibodies to Ion Channels
- Antibodies to Aquaporin (Water) Channels
- Antibodies
- Cell Biology
- Primary Antibodies
- Antibodies to Aquaporin (Water) ChannelsAntibodies
- Alphabetical Index
- Antibodies to Ion Channels
- Antibodies to Voltage-Gated Ion Channels
- W
