3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE
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- CAS-Nr.
- 335165-68-9
- Englisch Name:
- 3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE
- Synonyma:
- BAX CHANNEL BLOCKER;Bax channel blocke;)-3-(piperazin-1-yL;BAI1, 10 mM in DMSO;Baxchannelblocker2HCl;1-(3,6-Dibromo-9H-carbazoL;Bax channel blocker(BAI-1);BAI1 (Bax channel blocker);9H-Carbazole-9-ethanol, 3,6-dibromo-α-(1-piperazinylmethyl)-;1-(3,6-Dibromo-9H-carbazol-9-yl)-3-(piperazin-1-yl)propan-2-ol
- CBNumber:
- CB6143286
- Summenformel:
- C19H21Br2N3O
- Molgewicht:
- 467.2
- MOL-Datei:
- 335165-68-9.mol
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3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE Eigenschaften
- Siedepunkt:
- 388.1±42.0 °C(Predicted)
- Dichte
- 1.71±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- L?slichkeit
- ≥28.2 mg/mL in DMSO with ultrasonic; insoluble in EtOH; insoluble in H2O
- Aggregatzustand
- solid
- pka
- 14.48±0.20(Predicted)
- Farbe
- White
- InChI
- InChI=1S/C19H21Br2N3O.2ClH/c20-13-1-3-18-16(9-13)17-10-14(21)2-4-19(17)24(18)12-15(25)11-23-7-5-22-6-8-23;;/h1-4,9-10,15,22,25H,5-8,11-12H2;2*1H
- InChIKey
- HWFKCAFKXZFOQT-UHFFFAOYSA-N
- SMILES
- C12=CC=C(Br)C=C1C1=C(C=CC(Br)=C1)N2CC(O)CN1CCNCC1.Cl.Cl
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
Biologische Aktivit?t
Potent inhibitor of Bax-mediated mitochondrial cytochrome c release (IC 50 = 0.52 μ M). Suggested to inhibit Bax channel formation/activity.
3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 104)Lieferanten
335165-68-9()Verwandte Suche:
- Baxchannelblocker2HCl
- 3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE
- 3,6-Dibromo-α-(1-piperazinylmethyl)-9H-carbazole-9-ethanoldihydrochloride
- Bax channel blocke
- Bax channel blocker(BAI-1)
- 1-(3,6-Dibromo-9H-carbazoL
- 9H-Carbazole-9-ethanol, 3,6-dibromo-α-(1-piperazinylmethyl)-
- )-3-(piperazin-1-yL
- 1-(3,6-Dibromo-9H-carbazol-9-yl)-3-(piperazin-1-yl)propan-2-ol
- BAI1 (Bax channel blocker)
- "(+/-)-1-(3,6-dibromocarbazol-9-yl)-3-piperazin-1-ylpropan-2-ol"
- BAX CHANNEL BLOCKER
- Inhibitor,mitochondrial,cell,inhibit,BAI1,effector,BAI 1,critical,BAX,death,BAI-1,Bcl-2 Family,pathway,Apoptosis
- BAI1, 10 mM in DMSO
- 335165-68-9
- 335165-69-9
- C19H21Br2N3O2HCl
- Caspases/Apoptosis
- Apoptosis Inhibitors
