(R)-(4-Oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium-4-oxid
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- CAS-Nr.
- 63-89-8
- Bezeichnung:
- (R)-(4-Oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium-4-oxid
- Englisch Name:
- 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
- Synonyma:
- DPPC;COLFOSCERIL PALMITATE;1,2-DIHEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;1,2-dipalmitoyl-sn-glycero-3-PC;16:0 PC;DIPALMITOYL LECITHIN;L-A-LECITHIN DIPALMITOYL;DIPALMITOYL-L-ALPHA-LECITHIN;B,G-DIPALMITOYL-L-A-LECITHIN;L-ALPHA-LECITHIN, DIPALMITOYL
- CBNumber:
- CB6164209
- Summenformel:
- C40H80NO8P
- Molgewicht:
- 734.04
- MOL-Datei:
- 63-89-8.mol
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(R)-(4-Oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium-4-oxid Eigenschaften
- Schmelzpunkt:
- 229-229.5 °C
- alpha
- D23 +6.6° (c = 4.2 in 1:1 chloroform-methanol)
- storage temp.
- -20°C
- L?slichkeit
- Chloroform (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Biologische Quelle
- synthetic
- Merck
- 14,2477
- Stabilit?t:
- Stable. Incompatible with strong oxidizing agents.
- Kosmetik-Inhaltsstoffe Funktionen
- SKIN CONDITIONING
- InChIKey
- KILNVBDSWZSGLL-KXQOOQHDSA-N
- SMILES
- [C@@H](OC(=O)CCCCCCCCCCCCCCC)(COC(=O)CCCCCCCCCCCCCCC)COP([O-])(=O)OCC[N+](C)(C)C |&1:0,r|
- CAS Datenbank
- 63-89-8(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| S-S?tze: |
24/25 |
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| WGK Germany |
3 |
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| F |
10-21 |
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| HS Code |
29232000 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
 
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H331 |
Giftig bei Einatmen. |
Akute Toxizit?t inhalativ |
Kategorie 3 |
Achtung |
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P261, P271, P304+P340, P311, P321,P403+P233, P405, P501 |
| H336 |
Kann Schl?frigkeit und Benommenheit verursachen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Schl?frigkeit und Benommenheit) |
Warnung |
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P261, P271, P304+P340, P312,P403+P233, P405, P501 |
| H351 |
Kann vermutlich Krebs verursachen. |
Karzinogenit?t |
Kategorie 2 |
Warnung |
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P201, P202, P281, P308+P313, P405,P501 |
| H372 |
Sch?digt bei Hautkontakt und Verschlucken die Organe bei l?ngerer oder wiederholter Exposition. |
Spezifische Zielorgan-Toxizit?t (wiederholte Exposition) |
Kategorie 1 |
Achtung |
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P260, P264, P270, P314, P501 |
| H412 |
Sch?dlich für Wasserorganismen, mit langfristiger Wirkung. |
Langfristig (chronisch) gew?ssergef?hrdend |
Kategorie 3 |
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P273, P501 |
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| Sicherheit |
| P201 |
Vor Gebrauch besondere Anweisungen einholen. |
| P273 |
Freisetzung in die Umwelt vermeiden. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P308+P313 |
BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
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(R)-(4-Oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium-4-oxid Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
white powder
Verwenden
1,2-dipalmitoyl-sn-glycero-3-phosphocholine is a major phospholipid constituent and primary surface tension lowering component of natural lung surfactant. Colfosceril Palmitate is used as pulmonary surfactant and diagnostic aid (fetal lung maturity).
Definition
ChEBI: A phosphatidylcholine 32:0 in which the 1- and 2-acyl groups are specified as hexadecanoyl (palmitoyl). A synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of pulmonary surfactants.
Allgemeine Beschreibung
1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
l?uterung methode
It has three crystalline forms 1, 2 and ' which change at 60-70o and at 229o, respectively. In order to obtain a fine powder, ~2 g are dissolved in CHCl3 (15mL) and pet ether (b 35-60o) is added; the solution is evaporated to dryness in vacuo at <20o and then dried at 0.1mm over CaCl2. [Baer & Maurukas J Am Chem Soc 74 158 1952, Baer & Kates J Biol Chem 185 615 1950, Beilstein 4 IV 1463.]
(R)-(4-Oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium-4-oxid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(R)-(4-Oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium-4-oxid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 356)Lieferanten
63-89-8((R)-(4-Oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium-4-oxid)Verwandte Suche:
- 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
- LIPOID PE 180/180-PEG
- 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine,1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine, L-α-Phosphatidylcholine, dipalmitoyl
- L-alpha-DipalMitoyl phosphatidylcholine, 98% 500MG
- (7R)-4-Hydroxy-N,N,N-triMethyl-10-oxo-
7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacosan-1-aMiniuM Inner Salt 4-Oxide
- 1,2-Bis(hexadecanoyl)-sn-glycero-3-phosphocholine
- 1,2-Bis(pal
- 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine
2,3-Bis(palmitoyloxy)propyl [2-(Trimethylammonio)ethyl]phosphate
- L-b,g-DipalMitoyl-a-lecithin, DPPC
- DPPC L-1116
- (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]- 3,5,9-trioxa-4-phosphapentacosan-1-aminium 4-oxide, inner salt
- 1,2-Dihexadecanoyl-sn-glycero-3-phosphorylcholine
- 1,2-Dipalmitoyl-L-lecithin
- L-α-Phosphatidylcholine, dipalmitoyl
- L-β,γ-Dipalmi
- (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]- 3,5,9-trioxa-4-phosphapentacosan-1-aminium 4-oxide, inner salt 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine 1,2-Dihexadecanoyl-sn-glycero-3-phosph
- 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO
- L-alpha-Dipalmitoyl lecithin
- 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, SEMISYNTHETIC 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, SEMISYNTHETIC 1
- 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIPALMITOYL-SN-GLYCERO-3-PH
- L-A-DIPALMITOYL LECITHIN
- L-a-Lecithin-b,g-dipalmitoyl=DilinoleoylLecithin=Dilinoleoyl-L-a-Lecithin=L-b,g-Dipalmitoyl-a-Lecithin
- LecithinL-a-Dipalmitoyl
- L-ALFA-PHOSPHATIDYLCHLOLINE, DIPALMITOYL
- [2-[(R)-2,3-Bis[(1-oxohexadecyl)oxy]propyloxyphosphinatooxy]ethyl]dimethylmethanaminium
- L-alpha-Dipalmitoyl phosphatidylcholine,98%
- Colfosceril
- 3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-(1-oxohexadecyl)oxy-, inner salt, 4-oxide, (7R)-
- 3-sn-phosphatidylcholine, 1,2-dipalmitoyl
- 2-[[(2R)-2,3-dihexadecanoyloxypropoxy]-oxido-phosphoryl]oxyethyl-trimethyl-azanium
- Dipalmitoyl-L-ALPHA-phosphatidyl choline
- L-á-Phosphatidylcholine dipalmitoyl
- Dipalmitoyl-D62-SN-Glycero-3-Phospho-Choline
- 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine, L-α-Phosphatidylcholine, dipalmitoyl
- Coifosceril Palmitate
- Dipalmitoyl-L-α-glycerylphosphorylcholine
- ExosurfNeonatal
- 1,2-dipalmitoyl-sn-glycero-3-phosphocholine(DPPC)
- CAS_63-89-8
- Dipalmitoyl sn
- 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine (Colfosceril Palmitate)
- 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine>
- 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOL
- 129Y83
- 16:0 PC (DPPC)
- L-A-PHOSPHATIDYLCHOLINE, DIPALMITOYL (DPPC) (DIPALMITOYL-D62, 98%)
- L-DPPC
- 2,3-Bis(palmitoyloxy)propyl [2-(Trimethylammonio)ethyl] Phosphate
- 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE USP/EP/BP
- 1,2-DIHEXADECANOYL-SN-GLYCERO-3-
- 1，2-dipalmitoyl-sn-glycero-3-phosphocholine,≥99%
- 1,2-dipalmitoyl-sn-glycero-3-phosphpcholine
- 63-89-8 C40H80NO8P 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
- 16:0 PC
- 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
- 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE
- L-A-LECITHIN DIPALMITOYL
- L-ALPHA-DIPALMITOYL PHOSPHATIDYLCHOLINE
