Reversan

313397-13-6

CAS-Nr.: 313397-13-6

Englisch Name:: Reversan

Synonyma:: CBLC4H10;Reversan;Reversan, MRP1 and P-glycoprotein inhibitor;N-(3-Morpholinopropyl)-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-(4-morpholinyl)propyl]-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide;Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[3-(4-morpholinyl)propyl]-5,7-diphenyl-;5,7-Diphenyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (3-morpholin-4-yl-propyl)-amide;ReversanQ: What is Reversan Q: What is the CAS Number of Reversan Q: What is the storage condition of Reversan Q: What are the applications of Reversan

CBNumber:: CB61883226

Summenformel:: C26H27N5O2

Molgewicht:: 441.52

MOL-Datei:: 313397-13-6.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 70

Reversan Eigenschaften

Schmelzpunkt:: 176-180°C

Dichte: 1.26±0.1 g/cm3(Predicted)

storage temp.: Store at RT

L?slichkeit: DMSO: ≥8mg/mL at ~60°C

pka: 11.33±0.46(Predicted)

Aggregatzustand: powder

Farbe: faint yellow to yellow

InChI: 1S/C26H27N5O2/c32-26(27-12-7-13-30-14-16-33-17-15-30)22-19-28-31-24(21-10-5-2-6-11-21)18-23(29-25(22)31)20-8-3-1-4-9-20/h1-6,8-11,18-19H,7,12-17H2,(H,27,32)

InChIKey: JTRXWCLQFAZHGP-UHFFFAOYSA-N

SMILES: O=C(NCCCN1CCOCC1)c2cnn3c(cc(nc23)-c4ccccc4)-c5ccccc5

Sicherheit

WGK Germany	3
Speicherklasse	11 - Combustible Solids

Reversan Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Reversan represents a new class of nontoxic MRP1 inhibitor, which may be clinically useful for the treatment of neuroblastoma.

Biologische Aktivit?t

Selective inhibitor of multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (P-gp). Increases the sensitivity of MRP1-overexpressing tumor cells (MCF7/VP) to doxorubicin , vincristine and etoposide by 3.8-, 14.6- and 11.6-fold respectively. Increases the efficacy of vincristine and etoposide in murine models of neuroblastoma in vivo . Displays at activity on MRP2, MRP3, MRP5 and MRP5 transporters.

Reversan Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Reversan Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 70)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32468	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39037	58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd	+86-13119157289	18791163155@163.com	China	3397	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15838	69
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32321	50
SHANGHAI FORTUNE CHEMICAL TECHNOLOGY CO., LTD	13816107857	sales@fortunechem-sh.com	China	981	58
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8447	60
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9804	58

N-[3-(4-morpholinyl)propyl]-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
Reversan
CBLC4H10
5,7-Diphenyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (3-morpholin-4-yl-propyl)-amide
Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[3-(4-morpholinyl)propyl]-5,7-diphenyl-
ReversanQ: What is Reversan Q: What is the CAS Number of Reversan Q: What is the storage condition of Reversan Q: What are the applications of Reversan
Reversan, MRP1 and P-glycoprotein inhibitor
N-(3-Morpholinopropyl)-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
313397-13-6
C26H27N5O2
Aromatics
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals

一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线