R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride

125941-87-9

CAS-Nr.: 125941-87-9

Englisch Name:: R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride

Synonyma:: R(+)-SCH-23390;SCH 23390(HCI);SCH 23390 hydrochlor;SCH 23390 HYDROCHLORIDE;SCH 23390 hydrochloride NEW;SCH-23390 hydrochloride ，S0476;SCH-23390 hydrochloride, 10 mM in DMSO;(+)-SCH23390 Hydrochloride, 98.0+ % (HPLC);R(+)-SCH-23390 HYDROCHLORIDE SELECTIVE D 1 DOPAMINE;SCH23390 HYDROCHLORIDE; SCH-23390 HYDROCHLORIDE; R-(+)-SCH23390 HYDROCHLORIDE

CBNumber:: CB62131148

Summenformel:: C17H18ClNOHCl

Molgewicht:: 324.24

MOL-Datei:: 125941-87-9.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 111

R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride Eigenschaften

alpha: +27～+31°(D/20℃)(c=0.5,DMF)

storage temp.: protect from light

L?slichkeit: H2O: >5mg/mL

Aggregatzustand: solid

Farbe: white

Optische Rotation: [α]/D +32.1°, c = 1 in DMF(lit.)

Wasserl?slichkeit: water: 100mM

InChI: 1S/C17H18ClNO.ClH/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12;/h2-6,9-10,15,20H,7-8,11H2,1H3;1H/t15-;/m1./s1

InChIKey: OYCAEWMSOPMASE-XFULWGLBSA-N

SMILES: Cl[H].CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c3ccccc3

EPA chemische Informationen: (5R)-8-Chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol hydrochloride (125941-87-9)

Sicherheit

WGK Germany	3
Speicherklasse	13 - Non Combustible Solids

R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

A selective dopamine D1 receptor antagonist.

Biologische Aktivit?t

Potent D 1 antagonist (K i values are ~ 0.2, 0.3, ~ 1100, ~ 800 and ~ 3000 nM at D 1 , D 5 , D 2 , D 3 and D 4 receptors respectively). Also an agonist at 5-HT 1C/2C receptors (K i = 6.3 nM) in vitro .

Biochem/physiol Actions

R(+)-SCH-23390 hydrochloride is a selective D1 dopamine receptor antagonist. It has greater binding capacity towards 5-hydroxytryptamine 2 (5-HT2) and 5-HT1C serotonin receptor subtypes in in vitro. R(+)-SCH-23390 has a half-life of about 25 minutes after administration. It is known to possess anti-stereotypic effect and cataleptogenic effect. It also has inhibitory effect on motor activity.

R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 111)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39037	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+86-18621343501; +undefined18621343501	product@acmec-e.com	China	33324	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	+8613817748580	cooperation@kean-chem.com	China	40066	58
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2922	55
J & K SCIENTIFIC LTD.	18210857532; 18210857532	jkinfo@jkchemical.com	China	96815	76

125941-87-9()Verwandte Suche:

6-Chlor-m-kresol 4-Chlor-β-methylphenethylaminhydrochlorid 2-Chlor-4,5-xylenol p-Chlorphenethylamin Ethyl(1-phenylethyl)benzol

R(+)-7-CHLORO-8-HYDROXY-3-METHYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROCHLORIDE
SCH 23390 HYDROCHLORIDE
R(+)-SCH-23390 HYDROCHLORIDE SELECTIVE D 1 DOPAMINE
(5R)-8-Chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol hydrochloride
SCH 23390(HCI)
(+)-SCH23390 Hydrochloride, 98.0+ % (HPLC)
R(+)-SCH-23390
R(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine
SCH23390 HYDROCHLORIDE; SCH-23390 HYDROCHLORIDE; R-(+)-SCH23390 HYDROCHLORIDE
SCH 23390 hydrochloride NEW
SCH 23390 hydrochlor
(R)-8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol hydrochloride
SCH-23390 hydrochloride, 10 mM in DMSO
SCH-23390 hydrochloride ，S0476
125941-87-9
Dopamine receptor
Aromatics
Chiral Reagents
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals

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