(7BR,10AR)-2,3,4,7B,8,9,10,10A-OCTAHYDRO-1H-CYCLOPENTA[B][1,4]DIAZEPINO[6,7,1-HI]INDOLE HYDROCHLORIDE

428868-35-3

CAS-Nr.: 428868-35-3

Englisch Name:: (7BR,10AR)-2,3,4,7B,8,9,10,10A-OCTAHYDRO-1H-CYCLOPENTA[B][1,4]DIAZEPINO[6,7,1-HI]INDOLE HYDROCHLORIDE

Synonyma:: WAY163909 HCl;WAY-163909 hydrochloride;(7bR,10aR)-2,3,4,7B,8,9,10,10a-Octahydro-1H-cyclopenta[b][1,4]diazepino[6,7,1-hi]indole;(7BR,10AR)-2,3,4,7B,8,9,10,10A-OCTAHYDRO-1H-CYCLOPENTA[B][1,4]DIAZEPINO[6,7,1-HI]INDOLE HYDROCHLORIDE;(8aR,11aR)-4,5,6,7,8a,10,11,11a-Octahydro-9H-cyclopenta[4,5]pyrrolo[3,2,1-jk][1,4]benzodiazepine hydrochloride

CBNumber:: CB62468729

Summenformel:: C14H18N2.ClH

Molgewicht:: 250.771

MOL-Datei:: 428868-35-3.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 10

(7BR,10AR)-2,3,4,7B,8,9,10,10A-OCTAHYDRO-1H-CYCLOPENTA[B][1,4]DIAZEPINO[6,7,1-HI]INDOLE HYDROCHLORIDE Eigenschaften

storage temp.: room temp

L?slichkeit: H₂O: 2?mg/mL, clear

Aggregatzustand: powder

Farbe: white to beige

Wasserl?slichkeit: H2O: 2mg/mL, clear

InChI: 1S/C14H18N2.ClH/c1-3-10-9-15-7-8-16-13-6-2-4-11(13)12(5-1)14(10)16;/h1,3,5,11,13,15H,2,4,6-9H2;1H/t11-,13-;/m1./s1

InChIKey: UJVFYZZBCUXMDV-LOCPCMAASA-N

SMILES: Cl.N21[C@H]3[C@H](CCC3)c4c2c(ccc4)CNCC1

Sicherheit

WGK Germany	WGK 3
Speicherklasse	11 - Combustible Solids

(7BR,10AR)-2,3,4,7B,8,9,10,10A-OCTAHYDRO-1H-CYCLOPENTA[B][1,4]DIAZEPINO[6,7,1-HI]INDOLE HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Biochem/physiol Actions

WAY-163909 is a 5-hydroxytryptamine receptor 2C (5-HT2C) agonist (EC50/Emax = 8 nM/90% vs. 185 nM/40%/5-HT2B; Ki = 10.5 nM/5-HT2C, 212 nM/5-HT2A, 343 nM/5-HT7, 485 nM/5-HT2B, 245 nM/D4, 665 nM/rat α-1, >1 μM/5-HT1A, D2, D3, rat 5-HT-T) with no 5-HT2A-stimulatory potency. WAY-163909 exhibits anorectic (ED50 in mg/kg via i.p. = 1.4/DIO mice and 5.19/Zucker rats), antipsychotic (morphine-induced mouse climbing ID50 = 10.69 mg/kg i.p.; rat avoidance responding reduction ED50 = 1.27 mg/kg i.p. and 6.50 mg/kg p.o.) and antidepressant (10 mg/kg, i.p. or s.c. in forced rat swimming test ; 3 mg/kg/day i.p. in reducing olfactory bulbectomy/BULB-induced hyperactivity in rats) efficacy in vivo.

(7BR,10AR)-2,3,4,7B,8,9,10,10A-OCTAHYDRO-1H-CYCLOPENTA[B][1,4]DIAZEPINO[6,7,1-HI]INDOLE HYDROCHLORIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(7BR,10AR)-2,3,4,7B,8,9,10,10A-OCTAHYDRO-1H-CYCLOPENTA[B][1,4]DIAZEPINO[6,7,1-HI]INDOLE HYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 10)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Shanghai T&W Pharmaceutical Co., Ltd.	+86 21 61551611		China	9891	58
Porse Fine Chemical Co.,LTD	20-66003216 18666003216	info@porsefinechemical.com	China	1958	62
LETOPHARM LIMITED	+86-21-5821 5861	sales@letopharm.com	China	2384	58
Amatek Scientific Co. Ltd.	0512-56316828	info@amateksci.com	China	28769	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29867	58
Merck KGaA	--	ordercn@merckgroup.com	China	6394	58

(7BR,10AR)-2,3,4,7B,8,9,10,10A-OCTAHYDRO-1H-CYCLOPENTA[B][1,4]DIAZEPINO[6,7,1-HI]INDOLE HYDROCHLORIDE
WAY163909 HCl
(8aR,11aR)-4,5,6,7,8a,10,11,11a-Octahydro-9H-cyclopenta[4,5]pyrrolo[3,2,1-jk][1,4]benzodiazepine hydrochloride
(7bR,10aR)-2,3,4,7B,8,9,10,10a-Octahydro-1H-cyclopenta[b][1,4]diazepino[6,7,1-hi]indole
WAY-163909 hydrochloride
428868-35-3
C14H18N2HCl

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