BIIB-021
|
|
|
- CAS-Nr.
- 848695-25-0
- Englisch Name:
- BIIB-021
- Synonyma:
- 6-chloro-9-((4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl)-9H-purin-2-aMine;CS-479;CNF2024;BIIB-021;CNF-2024EC102;BIIB021 ，S1175;BIIB021/CNF2024;BIIB 021, ≥98%;BIIB021 BIIB-021;BIIB-021 USP/EP/BP
- CBNumber:
- CB62516264
- Summenformel:
- C14H15ClN6O
- Molgewicht:
- 318.76
- MOL-Datei:
- 848695-25-0.mol
|
BIIB-021 Eigenschaften
- Schmelzpunkt:
- 192-193℃
- Siedepunkt:
- 588.5±60.0 °C(Predicted)
- Dichte
- 1.50
- storage temp.
- -20°C
- L?slichkeit
- Soluble in DMSO (>25 mg/ml)
- Aggregatzustand
- solid
- pka
- 6.07±0.40(Predicted)
- Farbe
- White
- Stabilit?t:
- Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 montha.
- InChI
- InChI=1S/C14H15ClN6O/c1-7-4-17-9(8(2)11(7)22-3)5-21-6-18-10-12(15)19-14(16)20-13(10)21/h4,6H,5H2,1-3H3,(H2,16,19,20)
- InChIKey
- QULDDKSCVCJTPV-UHFFFAOYSA-N
- SMILES
- N1C2C(=NC(N)=NC=2Cl)N(CC2=NC=C(C)C(OC)=C2C)C=1
BIIB-021 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
BIIB 021 an orally available, fully synthetic small-molecule inhibitor of the heat shock protein Hsp90. Studies show that BIIB 021 adminisitration led to degradation of Hsp90 client proteins measured in tumor tissue and resulted in the inhibition of tumor growth in several human tumor xenograft models.
Definition
ChEBI: A member of the class of 2-aminopurines that is 2-aminopurine which is substituted by a chlorine at position 6 and by a (4-methoxy-3,5-dimethylpyridin-2-yl)methyl group at position 9.
BIIB-021 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
BIIB-021 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 169)Lieferanten
- CNF2024
- 9-[2-(2,2-diMethyl-propylaMino)ethyl]-8-(2-iodo-5-Methoxy-phenylsulfanyl)-9H-purin-6-ylaMine
- CNF-2024EC102
- 9H-Purin-2-aMine, 6-chloro-9-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]-
- BIIB-021
- BIIB021/CNF2024
- 6-Chloro-9-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]-9H-purin-2-amine
- 6-CHLORO-9-[(4-METHOXY-3,5-DIMETHYLPYRIDIN-2-YL)METHYL]PURIN-2-AMINE
- 6-Chloro-9-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]-9H-purin-2-amine BIIB 021
- BIIB 021 6-Chloro-9-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]-9H-purin-2-amine
- BIIB021(CNF2024)BIIB021
- BIIB021;BIIB-021; BIIB 021
- BIIB 021 (This product is only available in Japan.)
- BIIB 021, ≥98%
- BIIB-021 USP/EP/BP
- CS-479
- CNF2024; BIIB-021; BIIB 021; CNF 2024; CNF-2024
- CNF 2024 - BIIB 021
- BIIB021 BIIB-021
- BIIB021, 10 mM in DMSO
- BIIB021 ，S1175
- 6-Chloro-9-((3,5-dimethyl-4-methoxy-pyridin-2-yl)methyl)-9H-purin-2-ylamine
- 6-chloro-9-((4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl)-9H-purin-2-aMine
- 848695-25-0
- C14H15ClN6O
- Aromatics
- Heterocycles
- Inhibitors
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Antineoplastic
- Inhibitor
