ARRY-380
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- CAS-Nr.
- 937265-83-3
- Englisch Name:
- ARRY-380
- Synonyma:
- CS-523;Arry-830;ARRY-380;ARRY-380-d3;Arry-380, >=98%;HER2-Inhibitor-1;ARRY380; ARRY 380;ARRY-380 (analog );ARRY-380 USP/EP/BP;HER2-Inhibitor-1 ，S2752
- CBNumber:
- CB62554080
- Summenformel:
- C29H27N7O4S
- Molgewicht:
- 569.63
- MOL-Datei:
- 937265-83-3.mol
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ARRY-380 Eigenschaften
- Dichte
- 1.43
- storage temp.
- Store at -20°C
- L?slichkeit
- ≥28.5 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
- Aggregatzustand
- solid
- pka
- 6.34±0.19(Predicted)
- Farbe
- Light brown to brown
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
ARRY-380 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Arry-380 analog was designed as an inhibitor of EGFR (ErbB1).
Verwenden
ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM and also inhibits EGFR with IC50 of 4 μM.
ARRY-380 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
ARRY-380 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 103)Lieferanten
- ARRY-380 (analog )
- Arry-830
- ARRY-380;ARRY380; ARRY 380
- 6-[5-[[[2-(Methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]
- Arry-380, >=98%
- ARRY-380
- 6-[5-[[[2-(Methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4-quinazolinamine
- HER2-Inhibitor-1
- 6-[5-[[[2-(Methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4-quinazolinamine ARRY 380
- ARRY-380-d3
- N-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-Methylphenyl)-6-(5-(((2-(Methylsulfonyl)ethyl)aMino)Methyl)furan-2-yl)quinazolin-4-aMine
- CS-523
- ARRY380; ARRY 380
- 6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine
- 4-Quinazolinamine, 6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-
- ARRY-380 USP/EP/BP
- ARRY-380 (analog ), 10 mM in DMSO
- HER2-Inhibitor-1 ，S2752
- 937265-83-3
- C29H27N7O4S
- Inhibitors
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Sulfur & Selenium Compounds
