5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate
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- CAS-Nr.
- 52248-03-0
- Englisch Name:
- 5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate
- Synonyma:
- 4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidine-5-carbaldehyde;VHPOFDUCFKOUHV-XKGORWRGSA-O;S-(5'-Adenosyl)-L-methionine tosylate;S-(5''-Adenosyl)-L-methionine tosylate;P-toluenesulfonic acid adenosylmethionine;S-Adenosyl-L-Methionine p-Toluenesulfonic acid;P-toluenesulfonic acid adenosylmethionine (SAMe);S-(5''-Adenosyl)-L-methionine tosylate, 10 mM in DMSO;S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt;5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate
- CBNumber:
- CB62616975
- Summenformel:
- C22H30N6O8S2
- Molgewicht:
- 570.64
- MOL-Datei:
- 52248-03-0.mol
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5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate Eigenschaften
- Schmelzpunkt:
- 78℃
- storage temp.
- -20°C
- L?slichkeit
- DMF: 5 mg/ml; DMSO: 10 mg/ml; PBS (pH 7.2): 10 mg/ml
- Aggregatzustand
- A crystalline solid
- Farbe
- White to yellow
- Biologische Quelle
- synthetic (Organic)
- Wasserl?slichkeit
- H2O: 100mg/mL
- InChIKey
- VHPOFDUCFKOUHV-XKGORWRGSA-N
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
3 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
S-(5′-Adenosyl)-L-methionine
p-toluenesulfonate salt has been used for cell proliferation assay. It has also been used for methylation assay.
Allgemeine Beschreibung
S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt is used for the treatment of depression, liver cirrhosis, cholestasis and degenerative joint disease.
Biochem/physiol Actions
Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury.
5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 66)Lieferanten
- 5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate
- ((S)-3-Amino-3-carboxypropyl)(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonium 4-methylbenzenesulfonate
- VHPOFDUCFKOUHV-XKGORWRGSA-O
- S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt >=80% (HPLC), >=80% (spectrophotometric assay)
- P-toluenesulfonic acid adenosylmethionine
- P-toluenesulfonic acid adenosylmethionine (SAMe)
- S-(5'-Adenosyl)-L-methionine tosylate
- S-(5''-Adenosyl)-L-methionine tosylate
- S-(5''-Adenosyl)-L-methionine tosylate, 10 mM in DMSO
- S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt
- S-Adenosyl-L-Methionine p-Toluenesulfonic acid
- 4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidine-5-carbaldehyde
- 52248-03-0
- C15H23N6O5SC7H7O3SxC7H8O3S
