Glucagon
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- CAS-Nr.
- 16941-32-5
- Englisch Name:
- Glucagon
- Synonyma:
- Glucagon HCl;OXYNTOMODULIN;Glucagon (GLU);Glucagon (swine);HSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNKNNIA;Glucaton;Glucagon;GlucaGen;Glucagone;Glucagonum
- CBNumber:
- CB6299499
- Summenformel:
- C153H225N43O49S
- Molgewicht:
- 3482.75
- MOL-Datei:
- 16941-32-5.mol
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Glucagon Eigenschaften
- Dichte
- 1.53±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- L?slichkeit
- Practically insoluble in water and in most organic solvents. It is soluble in dilute mineral acids and in dilute solutions of alkali hydroxides.
- Aggregatzustand
- powder
- Farbe
- White to off-white
- Biologische Quelle
- synthetic
- Wasserl?slichkeit
- Soluble to 1 mg/ml in water
- InChIKey
- MASNOZXLGMXCHN-SXVMFYJYNA-N
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
3 |
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| F |
3-10-21 |
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| HS Code |
2937190000 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
 
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H317 |
Kann allergische Hautreaktionen verursachen. |
Sensibilisierung der Haut |
Kategorie 1A |
Warnung |
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P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
| H332 |
Gesundheitssch?dlich bei Einatmen. |
Akute Toxizit?t inhalativ |
Kategorie 4 |
Warnung |
|
P261, P271, P304+P340, P312 |
| H334 |
Kann bei Einatmen Allergie, asthmaartige Symptome oder Atembeschwerden verursachen. |
Sensibilisierung der Atemwege |
Kategorie 1 |
Achtung |
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P261, P285, P304+P341, P342+P311,P501 |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P271 |
Nur im Freien oder in gut belüfteten R?umen verwenden. |
| P272 |
Kontaminierte Arbeitskleidung nicht au?erhalb des Arbeitsplatzes tragen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P285 |
Bei unzureichender Belüftung Atemschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P304+P341 |
BEI EINATMEN: Bei Atembeschwerden an die frische Luft bringen und in einer Position
ruhigstellen, die das Atmen erleichtert |
| P321 |
Besondere Behandlung |
| P333+P313 |
Bei Hautreizung oder -ausschlag: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
| P342+P311 |
Bei Symptomen der Atemwege: GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P363 |
Kontaminierte Kleidung vor erneutem Tragen waschen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Glucagon Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
White or almost white powder
Verwenden
Glucagon is an Amino Acid sequence.
Definition
Produced by the α cells of the islands of Langerhans and also by the gastric mucosa. It is opposite in
effect to insulin. It appears to be a straight-chain polypeptide with a molecular weight of approximately 3500. Small amounts have been detected in comm
Biologische Funktion
Glucagon, a 29-amino-acid, straight-chain polypeptide of α-cell pancreatic origin, triggers liver
glycogenolysis and gluconeogenesis, thereby elevating glucose levels. The principal action of
glucagon is the liver-mediated release into the blood of abnormally high concentrations of
glucose, which causes hyperglycemia. This means that glucagon has an effect on blood glucose
levels that is opposite to what occurs with insulin.
Allgemeine Beschreibung
produced by recombinant DNA technology ismarketed by Novo Nordisk (glucagon [recombinant] hydrochloride,GlucaGen HypoKit, GlucaGen Diagnostic Kit)and by Eli Lilly (glucagon [recombinant] Emergency Kit).
Clinical Use
Endogenous glucagon isproduced from the gene-derived protein PG in the cells ofthe islets of Langerhans in the pancreas. The core functionof this hormone is to renormalize blood glucose levels whenthey fall too low, by stimulating production from glycogen stores in liver and muscle, and stimulating hepatic gluconeogenesis.Glucagon also elicits biochemical processes (suchas fatty acid oxidation) that supply the needed precursors forgluconeogenesis. Glucagon supplied exogenously (i.e., injected)in response to emergency hypoglycemia acts rapidlyto elicit these same responses. Clinically, glucagon also providesan alternative to cholinergic antagonists for reducingGI motility and secretory activity during radiologic imagingprocedures.
Glucagon Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Glucagon Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 362)Lieferanten
16941-32-5()Verwandte Suche:
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- GLUCAGON 1-37
- GLUCAGON (1-37) (PORCINE)
- GLUCAGON 37
- GLUCAGON ACETATE
- H-HIS-SER-GLN-GLY-THR-PHE-THR-SER-ASP-TYR-SER-LYS-TYR-LEU-ASP-SER-ARG-ARG-ALA-GLN-ASP-PHE-VAL-GLN-TRP-LEU-MET-ASN-THR-LYS-ARG-ASN-LYS-ASN-ASN-ILE-ALA-OH
- Glucagon 1-29
- Glucagon(1-29) Human HCl
- GLUCAGON FROM HOG PANCREAS, PACKAGE A 2 MG*
- Glucagon, non animal source
- GLUCAGON EXTRACTED FROM PORCINE*PANCREAS GAMMA-IRRA
- His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr
- Glucagon 1-29 acetate
- OXYNTOMODULIN (PORCINE)
- GASTRIN RELEASING PEPTIDE, PROCINE
- Glucagon【dog】
- L-His-L-Ser-L-Gln-Gly-L-Thr-L-Phe-L-Thr-L-Ser-L-Asp-L-Tyr-L-Ser-L-Lys-L-Tyr-L-Leu-L-Asp-L-Ser-L-Arg-L-Arg-L-Ala-L-Gln-L-Asp-L-Phe-L-Val-L-Gln-L-Trp-L-Leu-L-Met-L-Asn-L-Thr-OH
- Glucaton
- Glucagon (1-29) (human, rat, porcine)
- rGlucagon (2 x 2.94 mg) (recombinant Glucagon (Human)) (COLD SHIPMENT REQUIRED)
- Glucagon, USP
- rGlucagon, recombinant glucagon (human)
- Glucagon
- Glucagon (1-29), Human, Hydrochloride Salt
- Glucagon Hydrochlide
- GLP-1(7-37), Insulinotropin
- PORCINE GLUCAGON
- Glucagon,Porcine glucagon, >95%
- Glucagon Acetate/Hcl
- Glucagon(1-29) Human Hydrochloride
- 4-Amino-1-{5-O-[(9E)-9-octadecenoyl]-β-D-arabinofuranosyl}-2(1H)- pyrimidinone
- piperazine-2,5-dione dioxime
- Glucagon impurity
- Glucagon USP/EP/BP
- Glucagon,Porcine glucagon
- GlucagonTFA
- GlucagonQ: What is
Glucagon Q: What is the CAS Number of
Glucagon Q: What is the storage condition of
Glucagon Q: What are the applications of
Glucagon
- Glucagone
- Glucagonum
- Glucagon 4HCl
- GlucaGen
- Glucagon (HUMAN) (2 x 2.94 mg) (COLD SHIPMENT REQUIRED)
- Glukagon TFA
- Glucagon (1-29), bovine, human, rat, porcine
- Human Gucagon
- Glucagon RS
- Glucagon HCI
- HSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNKNNIA
- OXYNTOMODULIN
- Glucagon HCl
- Glucagon (swine)
- Glucagon (GLU)
- 16941-32-5
- GLUCAGON; GLUCAGON ACETATE
- 16941-35-2
- 6941-35-2
- C55H75N17O13C2H4O2
- C153H225N43O49S
- Amino Acid Derivatives
