Mepivacainhydrochlorid
|
|
|
- CAS-Nr.
- 1722-62-9
- Bezeichnung:
- Mepivacainhydrochlorid
- Englisch Name:
- Mepivacaine hydrochloride
- Synonyma:
- MEPIVACAINE HCL;N-(2,6-Dimethylphenyl)-1-methylpiperidine-2-carboxamide hydrochloride;Mepivacaine Impurity;Meaverin;Mepident;Optocain;Mepicaton;Chlorocain;Carbocaina;Scandonest
- CBNumber:
- CB6302306
- Summenformel:
- C15H22N2O.ClH
- Molgewicht:
- 282.81
- MOL-Datei:
- 1722-62-9.mol
|
Mepivacainhydrochlorid Eigenschaften
- Schmelzpunkt:
- 255-257°C (dec.)
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: soluble20mg/mL, clear
- Aggregatzustand
- powder
- Farbe
- white to beige
- Wasserl?slichkeit
- H2O: 20mg/mL, clear
- InChI
- InChI=1S/C15H22N2O.ClH/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3;/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18);1H
- InChIKey
- RETIMRUQNCDCQB-UHFFFAOYSA-N
- SMILES
- C1(=C(C)C=CC=C1C)NC(=O)C1CCCCN1C.Cl
- CAS Datenbank
- 1722-62-9(CAS DataBase Reference)
- EPA chemische Informationen
- 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride (1722-62-9)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
|
|
| R-S?tze: |
22 |
|
|
| S-S?tze: |
22-24/25 |
|
|
| RIDADR |
UN 2811 6.1 / PGIII |
|
|
| WGK Germany |
WGK 3 |
|
|
| RTECS-Nr. |
TK6475000 |
|
|
| TSCA |
TSCA listed |
|
|
| HS Code |
29333990 |
|
|
| Speicherklasse |
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects |
|
|
| Hazard Classifications |
Acute Tox. 3 Oral
STOT SE 3 |
|
|
| Toxizit?t |
LD50 in mice, rats (mg/kg): 280, 500 s.c. (Aberg) |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Achtung
|
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 3 |
Achtung |
|
P264, P270, P301+P310, P321, P330,P405, P501 |
| H336 |
Kann Schl?frigkeit und Benommenheit verursachen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Schl?frigkeit und Benommenheit) |
Warnung |
|
P261, P271, P304+P340, P312,P403+P233, P405, P501 |
|
| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P271 |
Nur im Freien oder in gut belüfteten R?umen verwenden. |
| P301+P310 |
BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
|
Mepivacainhydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
White Solid
Verwenden
Mepivacaine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.
Definition
ChEBI: The hydrochloride salt of mepivacaine. It is used as a local anaesthetic.
Biologische Funktion
Mepivacaine hydrochloride (Carbocaine) is longer
acting than lidocaine and has a more rapid onset of action
(3–5 minutes). Topical application is not effective.
It has been widely used in obstetrics, but its use has declined
recently because of the early transient neurobehavioral
effects it produces. Adverse reactions associated
with mepivacaine are generally similar to those
produced by other local anesthetics. It can be used with
epinephrine or levonordefrin (dental use only).
Allgemeine Beschreibung
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Mepivacaine hydrochloride is a local anesthetic that is related chemically and pharmacologically to the amide-type local anesthetics. It is often administered via local infiltration, peripheral nerve block, etc.
Sicherheitsprofil
skin irritant. Questionable carcinogen with
Mepivacainhydrochlorid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Mepivacainhydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 378)Lieferanten
1722-62-9(Mepivacainhydrochlorid)Verwandte Suche:
- Mepivacaine Hydrochloride (200 mg)
- Ropivacaine base Mepivacaine HCL
- (1-methyl-dl-piperidine-2-carboxylicacid)-2,6-dimethylanilidehydrochloride
- 1-methyl-2’,6’-pipecoloxylididehydrochloride
- Mepivacaine HCl USP
- 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride
- 2',6'-Pipecoloxylidide, 1-methyl-, monohydrochloride (6CI, 8CI)
- 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride (9CI)
- Carbocaina
- Carbocaine monohydrochloride
- Chlorocain
- Meaverin
- Mepicaton
- Mepident
- Mepivastesin
- Optocain
- Scandonest
- Mepivacaine HCL //Mepivacaine
- 1-Methyl-2μ,6μ-pipecoloxylidine hydrochloride, N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide hydrochloride
- Mepivacaine hydrochloride, >=99%
- LMW-Heparins
- 6’-pipecoloxylidide,1-methyl-2monohydrochloride
- carbocainehydrochloride
- dl-1-methyl-2’,6’-pipecoloxylididehydrochloride
- dl-mepivacainehydrochloride
- n-(2,6-dimethylphenyl)-1-methyl-2-piperidinecarboxamidmonohydrochloride
- 1-methyl-2',6'-pipecoloxylidine hydrochloride
- 1-METHYL-2',6'-PIPECOLOXYLIDINE HYDROCHLORIDE SALT
- MEPIVACAINE HYDROCHLORIDE, USP
- LABOTEST-BB LT00134661
- MEPIVACAINE HYDROCHLORIDE
- n-(2,6-dimethylphenyl)-1-methyl-2-piperidinecarboxamide hydrochloride
- N-(2,6-DIMETHYLPHENYL)-1-METHYL-2-PIPERIDINECARBOXAMIDE HYDROCHLORIDE SALT
- Mepivacaine hydrochloride, 99%, local anesthetic, voltage-gated Na+ channel blocker.
- Mepivacaine hydrochloride, BR
- Mepivacaine Hydrochloride >
- Mepivacaine HydrochL
- Ropivacaine EP Impurity C Racemate
- (+/-)-Mepivacaine hydrochloride
- Mepivacaine hydrochloride USP/EP/BP
- Mepivacaine Hydrochloride (1387002)
- Mepivacaine Impurity
- Mepivacaine HCI
- Mepivacaine hydrochloride salt
- Mepivacaine Impurity 2 HCl
- Mepivacaine HCl
IP/USP/BP/EP
- Mepivacaine Hydrochloride, ≥ 98.0%
- (±)-Mepivacaine hydrochloride
- (+/-)-Mepivacaine hydrochloride【SML1444】
- Mepivacaine HC
- MEPIVACAINE HCL
- N-(2,6-Dimethylphenyl)-1-methylpiperidine-2-carboxamide hydrochloride
- 1722-62-9
- 217-023-9
- Sodium channel
- Analgesic series
- Amines
- Aromatics
